洛匹那韦、利托那韦、氯喹、羟基氯喹和干扰素等有效治疗COVID-19的药物综述

J. Sujaritha, N. Deepasankar, K. Mathivathani, G. Aravindh, G. Gnanasekaran
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引用次数: 3

摘要

洛匹那韦(Lopinavir)、利托诺韦(Ritonovir)和干扰素(IFN)是主要通过蛋白酶抑制剂治疗HIV感染的抗病毒药物。氯喹和羟氯喹用于治疗疟疾引起的感染,如恶性疟原虫,以及自身免疫性疾病,如类风湿关节炎。氯喹对寄生虫有毒,使其无法消化宿主的血红蛋白,破坏病毒进入细胞的能力。抗病毒和抗疟药物是治疗COVID-19的一线药物治疗。这种疗法的目的是尽量减少症状,缩短病程。
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An overview of some drugs: Lopinavir, Ritonavir, Chloroquine, Hydroxy chloroquine and Interferon as a effective treatment against COVID-19
Lopinavir, Ritonovir and Interferon (IFN) are anti-viral drugs mainly used in the treatment of HIV infection by protease inhibitors. Chloroquine and Hydroxychloroquine are used in the treatment of malarial causing infection such as Plasmodium falciparum and also auto immune condition such as rheumatoid arthritis. Chloroquine makes toxic for the parasite to digest its host hemoglobin and disrupting the virus ability to enter the cell. The anti-viral and anti-malarial drugs are used in the first line drug therapy for the treatment of COVID-19. The aim of this therapy is to minimize the symptoms and shortens the duration of illness.
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