转铁蛋白受体在口腔肿瘤中的表达。

N Tanaka, T Miyamoto, M Saito, T Amagasa, S Shioda, Y Eishi, K J Hsieh
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引用次数: 0

摘要

用人转铁蛋白受体单克隆抗体染色检测口腔肿瘤组织中转铁蛋白受体的表达。阳性反应的细胞分布在正常上皮的基底层和准基底层。恶性肿瘤均可见染色,良性肿瘤未见染色。提示转铁蛋白受体的免疫组化分析除临床和病理检查外,对口腔恶性肿瘤的诊断有重要意义。
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Transferrin receptor expression in oral tumors.

Transferrin receptor expression in oral tumors was examined by staining with monoclonal antibody against the human transferrin receptor. The cells with positive reaction were recognized in the basal and parabasal layers of the normal epithelium. The staining was found in all the malignant tumors but not in the benign tumors. These results suggest that the immunohistochemical analysis of the transferrin receptor is useful for the diagnosis of oral malignant tumor in addition to the clinical and pathological examinations.

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