慢性活动性“类脂性”肝炎与HLA系统6例报告。

Y Horie, H Kawasaki, C Hirayama, A Suyama
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引用次数: 0

摘要

从1977年到1988年的12年间,鸟取大学医院在143例经组织学证实的慢性活动性肝炎患者中发现了6例(4.2%)慢性活动性“类脂性”肝炎。研究HLA抗原;bw22与cw1有较强的相关性,a11与日本罕见病有较强的相关性。这些结果提示,日本慢性活动性“类脂性”肝炎患者的HLA标记物与高加索患者不同,这可能是由于HLA系统中罕见的特异性,而不是不同的发病机制。
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Chronic active "lupoid" hepatitis and HLA system; report of 6 cases.

During the 12 years from 1977 to 1988 in Tottori University Hospital, 6 cases (4.2%) with chronic active "lupoid" hepatitis were encountered among 143 patients with histologically proven chronic active hepatitis. HLA antigens were studied; BW 22 and CW 1 were strongly associated, and A 11 was rather associated with the rare disorder in Japan. These results suggested that Japanese patients with chronic active "lupoid" hepatitis have different HLA markers from those in Caucasian patients, which may be attributable to rare specificity in the HLA system rather than different mechanisms of pathogenesis.

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