宽带相干拉曼成像的高速低噪声多通道系统

A. Ragni, G. Sciortino, M. Sampietro, G. Ferrari, A. Cadena, F. Vernuccio, G. Cerullo, D. Polli
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引用次数: 2

摘要

宽带相干拉曼光谱技术是一种非侵入性和非破坏性的光谱技术,在分子和生物化合物的分析中有着越来越广泛的应用。本文提出了第一个用于高速宽带拉曼成像的32-ch模块化平台,该平台能够同时获取和处理32个波长的光谱,具有多通道伪差分锁相结构,用于补偿激光源给出的多余噪声。该系统基于专门为宽带拉曼应用而设计的定制集成CMOS前端,以及用于并行采集和实时数据处理的Xilinx Artix-7 FPGA。实验结果表明,该系统能够达到弹丸噪声极限,获得像素停留时间为100μs的拉曼图像。
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High-Speed and Low-Noise Multichannel System for Broadband Coherent Raman Imaging
Broadband coherent Raman is a non-invasive and non-destructive spectroscopic technique with growing applications in the analysis of molecules and biological compounds. This paper presents the first 32-ch modular platform for highspeed Broadband Raman Imaging, able to simultaneously acquire and process 32 wavelengths of the spectrum with a multichannel pseudo-differential lock-in structure for the compensation of the excess noise given by the laser source. The system is based on a custom integrated CMOS front-end, specifically designed for Broadband Raman applications, and a Xilinx Artix-7 FPGA for the parallel acquisition and real-time data elaboration. Experimental results show that the system is able to reach the shot noise limit and acquire a Raman image with a pixel dwell time of 100μs.
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