菲律宾脑膜炎球菌病和传播:对近期数据的回顾

A. Ong-Lim
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摘要

本文回顾了菲律宾脑膜炎球菌病和传播的最新数据。它的目的是提供关于脑膜炎球菌病的流行病学、其传播、预防数据以及疫苗接种对疾病和传播的影响的信息。世界卫生组织认为菲律宾脑膜炎球菌病的流行率很低。然而,由于许多因素,目前的数据低估了该国的真实负担。近年来,菲律宾的数据显示病死率很高,因为只报告了败血症形式。关于无症状脑膜炎球菌携带率的研究很少,Gonzales等人的一项研究调查了生活在城市环境中的5-24岁菲律宾人的脑膜炎球菌鼻咽携带率。研究表明,总体携带率为3.7%,在10-14岁年龄组中最高(9%)。血清B组是最常见的分离物。有效的脑膜炎球菌疫苗是可用的。尽管不包括在国家免疫规划中,医学协会建议给感染高危人群接种疫苗。当地流行病学数据说明疾病和无症状携带是重要的,以加强未来规划的免疫和预防脑膜炎球菌病。
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Meningococcal Disease and Carriage in the Philippines: A Review of Recent Data
This article reviews recent data on meningococcal disease and carriage in the Philippines. It aims to provide information on the epidemiology of meningococcal disease, its carriage, data on prevention, and the impact of vaccination on disease and carriage. The World Health Organization considers the Philippines as having low endemicity for meningococcal disease. However, current data underestimates the true burden in the country due to many factors. In recent years, data from the Philippines show a high case-fatality rate since only the septicemic form is being reported. Studies on asymptomatic meningococcal carriage rates are sparse, with one study by Gonzales, et al. investigating the prevalence of meningococcal nasopharyngeal carriage in Filipinos aged 5-24 years old living in an urban setting. The study showed that the overall prevalence of carriage was 3.7% and was highest (9%) among the 10-14 age group. Serogroup B was the most common isolate. Effective meningococcal vaccines are available. Although not included in the National Immunization Program, medical societies recommend giving vaccines to individuals at high risk of infection. Data on local epidemiology accounting for the disease and asymptomatic carriage are important to strengthen future programs on immunization and prevention of meningococcal disease.
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