关于基因群问题

Sheng-Lung Peng, Yu-Lian Tang, Guanling Lee, Wei-Chun Liao
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引用次数: 0

摘要

基因网络分析是微阵列分析中最困难的工作之一。由于存在大量的基因连接关系,分析基因网络对于理解基因组的进化和功能是非常复杂的。基因组是保守基因簇的一个模型。然而,它是在线性结构的基因组上定义的。本文通过将基因网络转化为图,提出了基因群的概念,即按功能划分的封闭基因。提出了一项实验研究。我们认为这种图表方法可能对寻找封闭基因有用。
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On the gene group problem
The analysis of gene networks is one of the hardest works in microarray analysis. Due to a lot of gene connection relations, it is complicated to analyze gene networks for understanding the evolution and functions of genomes. Gene team is a model for conserved gene clusters. However, it is defined on a genome of linear structure. In this paper, by transforming a gene network to a graph, we propose the concept of a gene group, i.e., closed genes according to their functions. An experimental study is proposed. We think this graph approach may be useful for finding closed genes.
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