小鼠红细胞结合受体在人角质形成细胞上表达。

Dermatologische Monatschrift Pub Date : 1990-01-01
A Dobozy, J Hunyadi, B Bozoky, E Monostori, I Andó, A S Kenderessy, A Tiba
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引用次数: 0

摘要

免疫细胞和不同类型的表皮细胞具有相同的细胞表面抗原特征,如角化细胞与Leu 11 (CD16)单克隆抗体特异性反应,在γ -干扰素刺激后表达MHC II类和OKM5 (CD36)抗原。本研究提供的证据表明,人类角化细胞亚群最有可能在某一分化阶段,拥有小鼠红细胞结合受体,人类B淋巴细胞亚群的标记物。这一发现进一步证明了表皮和免疫系统之间的关系。
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The mouse erythrocyte binding receptor is expressed on human keratinocytes.

Immunocytes and different types of epidermal cells share cell surface antigen characteristics e.g. keratinocytes react specifically with the Leu 11 (CD16) monoclonal antibody and they express MHC class II and OKM5 (CD36) antigens after gamma-interferon stimulation. The present study provides evidence that a subpopulation of human keratinocytes most probably at a certain stage of differentiation, possesses the mouse erythrocyte binding receptor the marker of a human B lymphocyte subset. This finding is a further evidence for the relationship between the epidermis and the immune system.

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[Chondroid hidradenoma. Immunohistologic detection of cytokeratin and calmodulin]. [Cytokeratins--survey of incidence in normal and diseased skin. I. Cytokeratin expression in healthy skin]. [Cytokeratins--survey of incidence in normal and diseased skin. II. Cytokeratin expression in diseased skin]. [Bandage as a drug carrier--successful treatment of superficial thrombophlebitis with pentosan polysulfate]. [The keratinocyte--a biologically active cell].
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