肺炎患者抗生素使用情况评价

Nada Zavira, A. Jaelani, F. Herawati, R. Yulia
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引用次数: 4

摘要

肺炎是一种攻击肺组织(肺泡)的急性传染病,可由病毒、细菌或真菌感染引起。肺炎是印尼死亡风险最高的疾病之一。治疗肺炎的第一道防线是抗生素治疗。不当使用抗生素会增加抗生素耐药的可能性。抗菌药物控制规划(PPRA)是一项控制抗生素使用的卫生监测项目,其成功的标志是抗生素使用数量和质量的提高。可实施的抗生素控制是定量评价抗生素的使用和评价抗生素的适宜性。本研究的目的是以DDD/100病人-天为单位确定抗生素的使用数量以及基于PPAB的抗生素使用的适宜性。本研究为观察性研究,数据采用回顾性分析和描述性分析。研究材料使用了2020年1月至6月在孟加拉国RSUD的肺炎患者的病历数据。通过目的抽样获得符合纳入和排除标准的研究样本91份。采用DDD/100患者日单位和90% DU对数据进行定量分析,采用合适的适应症、合适的给药途径、合适的给药剂量、合适的给药间隔、合适的给药时间5个指标对抗生素的适宜性进行分析。结果显示,抗菌药物的总DDD/100患者-d为78.13 DDD/100患者-d,其中莫西沙星最高,为39.28 DDD/100患者-d。90%部分需要控制的抗菌药物为静脉注射莫西沙星(50.27%)、头孢曲松(23.34%)、阿奇霉素(6.83%)、口服莫西沙星(4.62%)、左氧氟沙星(3.85%)。基于PPAB RSUD Bangil 2019的抗生素适宜性显示:适应证正确(51.65%)、途径正确(100%)、剂量正确(87.23%)、时间间隔正确(48.93%)、给药时间正确(10.64%)。%)。
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Evaluation on The Use of Antibiotics for Pneumonia Patients
Pneumonia is an acute infectious disease that attacks lung tissue (alveoli) which can be caused by viral, bacterial, or fungal infections. Pneumonia is one of the diseases that have the highest death risk in Indonesia. The first line of treatment for pneumonia is antibiotic therapy. Inappropriate use of antibiotics will increase the possibility of antibiotic resistance. Antimicrobial Control Program (PPRA) is a health surveillance to control the use of antibiotics where the indicator of success is seen from the improvement in the quantity and quality of antibiotic use. Antibiotic control that can be performed is evaluating the use of antibiotics quantitatively and evaluating the suitability of antibiotics. The purpose of this study was to determine the quantity of antibiotic use with the DDD/100 patient-days unit and the suitability of the use of antibiotics based on PPAB. This study was observational, the data were taken retrospectively and analyzed descriptively. The research material used medical record data for pneumonia patients from January to June 2020 at RSUD Bangil. There were 91 research samples obtained by purposive sampling that met the inclusion and exclusion criteria. The data were analyzed quantitatively using the DDD/100 patient-days unit and 90% DU, and the suitability of antibiotics was analyzed using five indicators of the right indication, the right route, the right dose, the right interval, and the right time of administration. The results showed the use of antibiotics with a total value of DDD/100 patient-days of 78.13 DDD/100 patient-days with the highest value on moxifloxacin (39.28 DDD/100 patient-days). Antibiotics included in the 90% segment that need to be controlled are parenteral moxifloxacin (50.27%), ceftriaxone (23.34%), azithromycin (6.83%), oral moxifloxacin (4.62%), and levofloxacin (3.85%). The suitability of antibiotics based on PPAB RSUD Bangil 2019 showed the right indication (51.65%), right route (100%), right dose (87.23%), right interval (48.93%), and right time of administration (10.64). %).
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