显示对新一代抗生素耐药性的食物来源超级细菌的出现和分子力学特性

Sun-Hee Kim, Jong-Hyun Yoo, Jae-Soon Oh, Hataek Kwon, Young-Min Chi, Min-Hyeok Cha
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摘要

超级细菌是对抗菌素具有耐药性的细菌,它们的出现和广泛传播对人类构成了巨大威胁。开发新一代抗菌素是为了应对现有的抗菌素耐药性,但由于滥用抗菌素,耐药细菌立即出现并传播。特别是,食源性超级细菌是一个非常严重的问题,因为它们与人类的整体生活密切相关。本文通过对食源性耐粘菌素沙门氏菌和耐利奈唑胺肠球菌耐药性及分子流行病学传播途径的最新研究,探讨了两种细菌的分布及耐药水平。新一代抗菌剂的耐药因子在食物来源的超级细菌和其他环境之间的传播也得到了证实。因此,利用“一种健康计划”制定国家和全球耐药性监测项目变得越来越重要。
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차세대 항생제에 내성을 나타내는 식품 유래 슈퍼박테리아의 출현과 분자역학적 특성
Superbacteria are antimicrobial resistant bacteria, and their emergence and widespread became great threats to humanity. Next-generation antimicrobials were developed to deal with existing antimicrobial resistance, but resistant bacteria emerged and spread immediately due to indiscriminate use of antimicrobials. In particular, the foodborne superbacteria are highly serious problem because they are closely related to the overall human life. In this article, we explored the distribution and resistance level of foodborne colistin-resistant Salmonella and linezolid-resistant Enterococcus among through the latest research papers about their resistance and molecular epidemiological transmission route. The transmission of resistance factors between food-derived superbacteria and other environment was also confirmed for the case of next-generation antimicrobials. Therefore, it is increasingly important to develop national and global resistance monitoring projects with One-health scheme.
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