绿色技术合成席夫碱

Atul R Bendale
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引用次数: 0

摘要

从古至今,含席夫碱分子的化学性质一直是一个引人入胜的研究课题。它们被发现是一种灵活的药效团,用于创造和开发各种生物活性先导化合物。希夫碱是含有亚胺官能团的化合物。近年来合成和研究了不同的希夫碱副产物的抗氧化、抗菌、抗结核、抗炎、抗抑郁和抗焦虑、抗高血压、抗惊厥、抗癌和抗真菌活性。综述了希夫碱的固体合成、声化学合成、微波辅助合成等不同的绿色化学技术。
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Green Techniques to Synthesize Schiff Bases
From ancient times, the chemistry of Schiff base-containing molecules has been a fascinating subject of study. They've been found to be a flexible pharmacophore for the creation and development of a wide range of bioactive lead compounds. Schiff bases are compounds containing the imine functional group. Different Schiff base containing byproducts have recently been synthesized and studied for activities such as antioxidant, antibacterial, antituberculosis, anti-inflammatory, antidepressant and anxiolytic activity, antihypertensive, anticonvulsants, anticancer, and antifungal activity. Different green chemistry techniques like-solid state, sonochemical, microwave assisted synthesis for synthesis of Schiff bases are discussed in this review.
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