GENOTYPING AND SEROPREVALENCE OF TOXOPLASMA GONDII IN ABORTION WITH ELEVATION OF INTERLEUKIN-6 LEVEL

Toxoplasmosis is a harmful microorganism that resides inside the cells of the host and produces serious symptoms such as abortion. A total of (48) blood samples were taken from aborted women in this study, with (40) healthy persons serving as a control group. Between the 15th of January and the 30th of September 2021, the patients were treated at Al-Karkh Maternity Hospital. The infection rate was highest in the age range (18-25) years for both the infected women and the control group, according to the findings. Among aborted mothers with Toxoplasmosis, the IgG antibody positivity rate was 40 percent higher than the IgM antibody positivity rate, while the negative rate was 8 percent (16.6 percent ). When compared to healthy persons, there was a considerable increase in the frequencies of positive AntiToxoplasmosis IgM antibody (69.8%) and IL-6 (75%) when compared to healthy individuals. IL-6 had a greater prevalence of 36 (66.7%) than IgM (30%). (73.4 percent ). The ROC test was utilized to evaluate those two parameters. The fragment 96bp of the B1 gene of the DNA isolated was inflated using nested PCR test amplification. Ordinary PCR was performed to amplify the IL-6 gene in 431 bp of isolated DNA