热释光剂量计评价头颈部肿瘤调强放疗的表面剂量

O. Gül, Nihal Büyükçi̇zmeci̇, H. Başaran
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头颈部肿瘤患者放射治疗中表面剂量的准确估计对治疗具有重要意义。本研究的目的是利用热释光剂量计评估头颈癌调强放疗(IMRT)的表面剂量。此外,它的目的是检查表面剂量估计的治疗计划系统(TPS)在不同的网格大小。在对15例头颈癌患者进行计算机断层扫描(CT)之前,在颈部区域确定5个不同的点,并以不会产生伪影的方式进行标记。IMRT计划是为1.5和2.5毫米的网格尺寸创建的。获得表面剂量,用于计算颈部5个不同点的TPS和TLD。比较了不同网格尺寸下TLD测量和TPS计算得到的表面剂量。所有患者均接受3期适应性放疗(ART),每个方案重复表面剂量比较。根据方案0,1.5 mm和2.5 mm网格尺寸的TLD测量高度分别为4.06%和7.87%。在方案1中,1.5mm和2.5mm栅格时,TPS和TLD剂量差异分别为4.00%和8.15% (p=0.00和p=0.00)。对于计划2的剂量测量,在1.5mm和2.5mm栅格尺寸下,TPS和TLD的剂量差异分别为4.07%和9.96% (p=0.00和p=0.00)。在所有治疗方案的TLD测量中获得的表面剂量高于TPS剂量计算。头颈部肿瘤放射治疗中表面剂量的准确估计对治疗非常重要。用TPS计算的表面剂量通常低于规定剂量。因此,在评估放疗方案时,应考虑TPS低估了表面剂量。这个比率可以通过剂量测量来确定。热释光剂量计是这一过程的合适设备。
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Evaluation of Surface Dose for Intensity Modulated Radiotherapy of Head and Neck Cancer Using Thermoluminescent Dosimeters
Accurate estimation of the surface dose in radiotherapy of patients with head and neck cancer is very important in terms of treatment. The aim of this study is to evaluate the surface dose for intensity-modulated radiotherapy (IMRT) of head and neck cancer using thermoluminescent dosimeters (TLDs). In addition, it is aimed to examine the surface dose estimates of the treatment planning system (TPS) for different grid sizes. Before the computed tomography (CT) images were taken for 15 head and neck cancer patients, 5 different points determined in the neck region were marked in a way that would not cause artifacts. IMRT plans are created for 1.5 and 2.5 mm grid sizes. Surface doses were obtained for TPS calculations and TLD measurements at 5 different points in the neck region. Surface doses obtained from TLD measurements and TPS calculations with different grid sizes were compared. All patients received 3-stage adaptive radiotherapy (ART) and the surface dose comparison was repeated for each plan. According to plan 0, the height of TLD measurements for the 1.5 and 2.5 mm grid size were 4.06% and 7.87%, respectively. In Plan 1, the difference between TPS and TLD doses was 4.00% and 8.15% for grid size 1.5mm and 2.5mm, respectively (p=0.00 and p=0.00). For dose measurements from Plan 2, the difference between TPS and TLD doses was 4.07% and 9.96% for grid size 1.5mm and 2.5mm, respectively (p=0.00 and p=0.00). Surface doses obtained in TLD measurements for all treatment plans were higher than in TPS dose calculations. Accurate estimation of the surface dose in head and neck cancer radiotherapy is very important for treatment. Surface doses calculated with TPS are usually lower than the prescribed dose. Therefore, during the evaluation of radiotherapy plans, it should be considered that TPS underestimates the surface dose. This ratio can be determined by dosimetric measurements. Thermoluminescent dosimeters are suitable equipment for this process.
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