苦参根提取物的植物化学研究

Tewodroes Mulu, L. Adane, Dessalegn Bekele, Fillipo Tamru, Tizazu Sorsa
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摘要

Teclea nobilis是埃塞俄比亚的特有种之一。它是一种传统药物,用于治疗止痛药和其他疾病。虽然人们已经研究了许多种Teclea属植物的化学成分,但对Teclea nobilis根的化学成分的研究尚未见报道。对该植物的C6 H14、CH2 Cl2、CH2 Cl2 /CH3 OH(1:1)和CH3 OH根提取物进行植物化学筛选,发现其含有生物碱、黄酮类、萜烯类、酚类、单宁类和苷类化合物。采用CH2 Cl2 /CH3 OH(1:1)柱层析分离得到化合物TN1(0.06%)、TN2(0.04%)和TN3(0.05%)三个化合物。提出了化合物TN1和化合物TN2的结构,化合物TN3由于缺乏足够的光谱数据而没有完全表征。
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Phytochemical Investigation on The Root Extract of Teclea Nobilis
Teclea nobilis is one of an endemic species to Ethiopia. It is used as a traditional medicine to treat analgesics and other disorders. Although many species of the genus Teclea have been investigated for their chemical constituents, there is no much prior report on the investigation of chemical constituents of root of Teclea nobilis. Phytochemical screening of the C6 H14, CH2 Cl2 ,CH2 Cl2 /CH3 OH (1:1) and CH3 OH root extracts of the plant revealed the presence of alkaloids, flavonoids, terpenes, phenols, tannins and glycosides.Chromatographic separation using column chromatography of CH2 Cl2 /CH3 OH (1:1) result in isolation of three compounds namely compound TN1(0.06%), TN2(0.04%)and TN3(0.05%).Structure are proposed for Compound TN1 and compound TN2 .Compound TN3 was not fully characterized due to lack of adequate spectral data.
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