{"title":"凝血酶原时间升高:单克隆γ病的不寻常表现——一例报告和文献复习","authors":"R. M. M. Seelarathna, V. Sujanitha, T. Kumanan","doi":"10.4038/jmj.v33i2.139","DOIUrl":null,"url":null,"abstract":"Monoclonal Gammopathy of Undetermined Significance (MGUS) is one of the plasma cell dyscrasias. An isolated finding of a monoclonal para-protein in serum or urine is the hallmark finding in MGUS. Most often it is found incidentally during an unrelated medical evaluation and/ or investigation to find a cause for neuropathy, anaemia, rashes, vasculitis or elevated Erythrocyte Sedimentation Rate (ESR). This case report illustrates an evaluation of a patient with persistently elevated prothrombin time has eventually lead to a diagnosis of MGUS.","PeriodicalId":280534,"journal":{"name":"Jaffna Medical Journal","volume":"6 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Elevated Prothrombin Time: An unusual presentation of Monoclonal Gammopathy of Undermined Significance – A Case Report and literature review\",\"authors\":\"R. M. M. Seelarathna, V. Sujanitha, T. Kumanan\",\"doi\":\"10.4038/jmj.v33i2.139\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Monoclonal Gammopathy of Undetermined Significance (MGUS) is one of the plasma cell dyscrasias. An isolated finding of a monoclonal para-protein in serum or urine is the hallmark finding in MGUS. Most often it is found incidentally during an unrelated medical evaluation and/ or investigation to find a cause for neuropathy, anaemia, rashes, vasculitis or elevated Erythrocyte Sedimentation Rate (ESR). This case report illustrates an evaluation of a patient with persistently elevated prothrombin time has eventually lead to a diagnosis of MGUS.\",\"PeriodicalId\":280534,\"journal\":{\"name\":\"Jaffna Medical Journal\",\"volume\":\"6 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-12-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Jaffna Medical Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4038/jmj.v33i2.139\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jaffna Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4038/jmj.v33i2.139","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
单克隆性未确定意义γ病(Monoclonal Gammopathy of Undetermined Significance, MGUS)是浆细胞病变的一种。血清或尿液中单克隆副蛋白的分离发现是MGUS的标志性发现。大多数情况下,它是在不相关的医学评估和/或调查中偶然发现的,以寻找神经病变,贫血,皮疹,血管炎或红细胞沉降率升高(ESR)的原因。本病例报告说明了评估患者持续升高凝血酶原时间最终导致MGUS的诊断。
Elevated Prothrombin Time: An unusual presentation of Monoclonal Gammopathy of Undermined Significance – A Case Report and literature review
Monoclonal Gammopathy of Undetermined Significance (MGUS) is one of the plasma cell dyscrasias. An isolated finding of a monoclonal para-protein in serum or urine is the hallmark finding in MGUS. Most often it is found incidentally during an unrelated medical evaluation and/ or investigation to find a cause for neuropathy, anaemia, rashes, vasculitis or elevated Erythrocyte Sedimentation Rate (ESR). This case report illustrates an evaluation of a patient with persistently elevated prothrombin time has eventually lead to a diagnosis of MGUS.