具有3D聚焦和连续分选功能的微型分选机

T. Leu, Hung‐Ying Chen, F. Hsiao
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引用次数: 2

摘要

设计和研究了介电泳(DEP)流分选器,用于从多种样品的混合物中连续选择感兴趣的颗粒(细胞)。利用非均匀电场产生的DEP力作为约束力,将生物颗粒三维聚焦到单个颗粒流中,并利用偏转力对微分选机中的生物颗粒进行连续分选。通过数值模拟和实验研究,揭示了流动分选器对流体进行聚焦和分选的关键机理。
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Micro Sorters with 3D Focusing and Continuous Sorting
Dielectrophoretic (DEP) flow sorters for continuously selecting particles (cells) of interest from a mixture of many samples were designed and studied. DEP forces created by non-uniform electric fields are used as confining forces to three-dimensionally focus bio-particles into a single particle stream, as well as deflection forces to continuously sort the bio-particles in the micro sorter. The key mechanism of the flow sorters that can focus and sort particles against fluid flows is demonstrated numerically and experimentally.
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