超高剂量率x射线辐照灭菌医疗设备

N. Barinov, G.I. Dolgachev, D. D. Maslennikov, M.S. Nitishinsky, A. Ushakov, L.P. Zakatov, O. Zinoviev
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摘要

报告了在轫致辐射发生器RS-20上进行灭菌试验的结果。在10-30 kGy剂量水平的不同条件下,以1 MGy/s的峰值剂量率范围对各种微生物进行了测量。立即照射的体积为0.036立方米,体积中心提供平均剂量率为1 kGy/h。利用2.0 MeV、10 kA、100 ns脉冲电子束以2 Hz的频率射向靶体产生轫致辐射。并与使用相同剂量值的Co-60同位素在连续放射性核辐射源下同时进行的试验进行了比较。结果表明,使用1 MGy/s的峰值剂量率,在RS-20下,对放射性核源的完全灭菌效果只需减少2-5倍的剂量,并提高了系统的总效率。总剂量降低到5-12千吉,可以减少设备上的辐射负荷,扩大消毒应用的范围。
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Medical equipment sterilization using superhigh dose rate X-ray irradiation
The results of sterilization tests made at the RS-20 generator of Bremsstrahlung for sterilizing purpose are reported. The measurements were done under different conditions in the area of 10-30 kGy dose levels at 1 MGy/s peak dose rate range for various microorganisms. The immediately irradiated volume was 0.036 of cubic meter with average dose rate at 1 kGy/hour provided in the center of the volume. The Bremsstrahlung was created by 2.0 MeV 10 kA 100 ns pulsed e-beam directed toward the target at 2 Hz. The tests were compared with those made simultaneously at continuous radionucleic radiation source using Co-60 isotope providing same dose values. It was found that full sterilization effect at RS-20 using 1 MGy/s peak dose rate takes 2-5 times lesser dose against radionucleic source and increases total efficiency of the system. Total dose decrease down to 5-12 kGy allows to reduce radiation loads on the equipment and broadens the area of sterilizing application.
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