犬巴贝斯虫病急性和慢性病程血液血液学参数的变化

D. Chervyakov, S. Lutsuk, O. Dilekova, D. Proskurin
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As a result, it was revealed that in acute and chronic course there is a decrease in the number of eryth-rocytes to 4.756 ± 0.3149 * 1012 / l, which is lower than the reference values by 13.5%, and to 5.344 ± 0.781 * 1012 / l, which is lower by 2 , 8% respectively. There is also a decrease in hemoglobin in the acute course to 113.4 ± 7.567 g / l, or 5.5%, in the chronic course this hemato-logical indicator is within the reference values. A decrease in hematocrit is ob-served in both courses of babesiosis and amounts to 0.3252 ± 0.01925 l / l, which is 12.1% lower than the reference values in acute and up to 0.3496 ± 0.04137 l / l, or 5, 5% for chronic. Also, in the acute course of this disease, there is a decrease in leukocytes to 5.487 ± 0.4701 * 109 / l, which is 8.5% lower than the reference values. 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摘要

目前,根据非官方数据,在北高加索联邦区境内,即斯塔夫罗波尔市,大约有25万只家畜,其中包括大约8万只狗。侵袭性疾病感染占疾病总数的31-33%,其中包括血液寄生虫病,每100人感染9-11例。犬巴贝斯虫的入侵因季节而异,平均占疾病总数的4%。为此,研究了犬巴贝斯虫病急性和慢性病程的血液学参数。结果显示,在急性和慢性病程中,红细胞数量分别下降到4.756±0.3149 * 1012 / l,比参考值低13.5%,5.344±0.781 * 1012 / l,比参考值低2.8%。急性期血红蛋白降至113.4±7.567 g / l(5.5%),慢性期血红蛋白在参考值范围内。在巴贝斯虫病的两种病程中都观察到红细胞压积的下降,其值为0.3252±0.01925 l / l,比急性期的参考值低12.1%,比慢性期的参考值低0.3496±0.04137 l / l,或5.5%。在本病的急性病程中,白细胞下降到5.487±0.4701 * 109 / l,比参考值低8.5%。我们特别关注血小板计数的明显变化,发现血小板明显减少,血小板减少至26.67±2.8 * 109 / l,占86.6%,血小板减少至0.01973±0.005502个细胞/ l,比急性期参考值降低90.1%。在慢性病例中,血小板下降至116.8±10.97 * 109 / l(41.6%),血小板临界值下降至0.068±0.01794 / l(66%)。
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CHANGE IN BLOOD HEMATOLOGI-CAL PARAMETERS IN ACUTE AND CHRONIC COURSE OF BABESIOSIS IN DOGS
Currently, on the territory of the North Cau-casus Federal District, namely in the city of Stav-ropol, according to unofficial data, there are about 250 thousand domestic animals, including about 80 thousand dogs. Infection with invasive diseases accounts for 31-33% of the total number of diseases, which include blood-parasitic diseas-es, in the amount of 9-11 cases per 100 head. Invasion of Babesia canis varies depending on the season and averages 4% of the total number of diseases. In this regard, hematological parame-ters have been studied in acute and chronic course of babesiosis in dogs. As a result, it was revealed that in acute and chronic course there is a decrease in the number of eryth-rocytes to 4.756 ± 0.3149 * 1012 / l, which is lower than the reference values by 13.5%, and to 5.344 ± 0.781 * 1012 / l, which is lower by 2 , 8% respectively. There is also a decrease in hemoglobin in the acute course to 113.4 ± 7.567 g / l, or 5.5%, in the chronic course this hemato-logical indicator is within the reference values. A decrease in hematocrit is ob-served in both courses of babesiosis and amounts to 0.3252 ± 0.01925 l / l, which is 12.1% lower than the reference values in acute and up to 0.3496 ± 0.04137 l / l, or 5, 5% for chronic. Also, in the acute course of this disease, there is a decrease in leukocytes to 5.487 ± 0.4701 * 109 / l, which is 8.5% lower than the reference values. We paid special attention to the manifested changes in platelet counts, and re-vealed significant thrombocytopenia, in which there is a decrease in the number of platelets to 26.67 ± 2.8 * 109 / l, or 86.6%, as well as thrombocyte to 0.01973 ± 0.005502 cells / l, which is 90.1% lower than the reference values in acute course. And also in chronic cases, a decrease in platelets to 116.8 ± 10.97 * 109 / l, or 41.6%, and thrombocrit to 0.068 ± 0.01794 cells / l, or 66%, re-spectively, was revealed.
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