小于胎龄婴儿出生的风险分析

Masamitsu Nakamura, J. Hasegawa, Ryu Matsuaka, T. Mimura, K. Ichizuka, A. Sekizawa, T. Okai
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引用次数: 3

摘要

目的:探讨具有危险因素的小胎龄儿(SGA)出生的可能性。方法:本研究招募了2005年至2007年间出生的3046名婴儿。将病例分为小胎龄组(SGA) 312例和对照组(2734例)。通过多变量分析回顾性分析低出生体重的相关因素,包括新生儿、胎盘和脐带的异常以及母体并发症。结果:多胎妊娠SGA的优势比(99%置信区间)为5.3(3.4 ~ 8.3),胎儿畸形2.4(1.2 ~ 4.7),膜状脐带插入4.6(2.0 ~ 10.5),边缘脐带插入2.0(1.0 ~ 3.8),高卷脐带3.7(2.0 ~ 6.9),妊高征5.3(3.2 ~ 9.0),低母体体重指数(BMI<18.5)的优势比为1.8(1.2 ~ 2.6)。结论:我们进行了多变量分析,以确定SGA婴儿出生的优势比-胎儿生长受限的各种危险因素。这些数据可以通过加强围产儿管理来改善婴儿的预后。
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Risk Analysis For The Birth Of A Small For Gestational Age (SGA) Infant
Objectives: To investigate the possibility of the births of small for gestational age (SGA) infant in patients with risk factors.Methods: This study enrolled 3046 babies born between 2005 and 2007. The cases were divided into the small for gestational age (SGA) group (312 cases) and the control group (2734 cases). A multivariable analysis was conducted to retrospectively analyze the factors associated with low fetal birth weight, which include abnormalities of the neonate, placenta and umbilical cord, and maternal complications.Results: The odds ratios (99% confidence interval) of SGA were 5.3 (3.4-8.3) for multiple pregnancy, 2.4 (1.2-4.7) for fetal malformation, 4.6 (2.0-10.5) for velamentous cord insertion, 2.0 (1.0-3.8) for marginal cord insertion, 3.7(2.0-6.9) for hypercoiled cord, 5.3 (3.2-9.0) for pregnancy induced hypertension, and 1.8 (1.2-2.6) for low maternal body mass index (BMI<18.5). Conclusion: A multivariable analysis was conducted to determine the odds ratios for the birth of an SGA infant -for various risk factors of fetal growth restriction. These data might improve the prognosis of infants through the intensive perinatal management.
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