软组织复合材料弹性体生物3D打印人工肌腱的设计、仿真与制造

Pasin Kuncharin, S. Boonyagul, N. Tanadchangsaeng, T. Tawonsawatruk
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引用次数: 0

摘要

最近,研究人员正在尝试使用3D生物打印作为关键平台,制造人工肌腱,与患者自身撕裂的肌腱复合,以帮助他们恢复速度。在这项工作中,可以进行肌腱的设计和模拟,以研究人工肌腱的力学性能。利用三维工件设计软件Solid Work程序进行制作,直至获得符合手外科医生要求的肌腱形状,完成了3种形式。将3种人工肌腱进行力学性能对比仿真后,4.0 mm宽度和1.0 mm孔径的条件尺寸可以为实际肌腱原型的成型提供最合适的机械强度。此外,我们还成功地利用弹性聚合物3D生物打印技术制造了肌腱原型材料。
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Design Simulation and Fabrication of 3D Bioprinting Artificial Tendon from Elastomer for Soft Tissue Composite
Recently, researchers are trying use 3D bioprinting as a key platform to make artificial tendons for being composite with patients' own teared tendon to help their recovery speed. In this work, tendon design and simulation could be processed to investigate the mechanical properties of artificial tendons. It could be fabricated by using Solid Work program which is a software for designing 3D workpieces until we obtained the tendon shape as according to the requirement of hand surgeon which accomplished in all 3 forms. After bringing all 3 artificial tendons to simulation by comparing the mechanical properties, the condition size of 4.0-mm width and 1.0-mm of hole diameter could provide the most suitable mechanical strength for forming the actual tendon prototype. Moreover, we have also successfully fabricated the tendon prototype material using 3D bioprinting with elastomeric polymer.
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