长冠肺炎探索性因素分析

Joseph A. Dorri, Leonard A. Jason
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引用次数: 2

摘要

探索性因素分析(EFA)可以提供一个窗口,以了解疾病的潜在维度,例如长冠状病毒。发现Long COVID的潜在因素使研究人员和临床医生能够更好地概念化,研究和治疗这种疾病。在这项研究中,参与者是从专门针对COVID和Long COVID的社交媒体网站上招募的。在480名参与者中,完成至少90%的调查,自COVID-19症状出现以来报告症状两个月或更长时间,并且未因COVID而住院的人被纳入EFA。自首次症状出现以来的平均持续时间为74.0(37.3)周。一份名为“德保罗症状问卷-COVID”的新问卷用于评估最近一个月出现的38种长COVID症状的频率和严重程度的自我报告。最沉重的症状是“身体或精神活动后症状加重(也称为劳累后不适)”、“疲劳/极度疲劳”、“思维困难和/或注意力集中”、“睡眠问题”和“肌肉疼痛”。EFA的结果是一个三因素模型,其中一般、PEM/疲劳/认知功能障碍和心理因素分别由16项、6项和3项组成(共25项)。采用劈半信度检验,EFA项目的信度为0.90。最后,通过三个EFA因素分析参与者自我报告的功能损害水平。本文提供了对研究和实践的解释和应用。
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AN EXPLORATORY FACTOR ANALYSIS OF LONG COVID
An exploratory factor analysis (EFA) can provide a window into the latent dimensions of a disease, such as Long COVID. Discovering the latent factors of Long COVID  enables researchers and clinicians to better conceptualize, study and treat this disease. In this study, participants were recruited from social media sites dedicated to COVID and Long COVID. Among the 480 participants, those who completed at least 90% of the survey, reported symptoms for two or more months since COVID-19 symptom onset, and had not been hospitalized for COVID were used in the EFA. The mean duration since initial symptom onset was 74.0 (37.3) weeks. A new questionnaire called The DePaul Symptom Questionnaire-COVID was used to assess self-reports of the frequency and severity of 38 Long COVID symptoms experienced over the most recent month. The most burdensome symptoms were “Symptoms that get worse after physical or mental activities (also known as Post-Exertional Malaise),” “Fatigue/extreme tiredness,” “Difficulty thinking and/or concentrating,” “Sleep problems,” and “Muscle aches.” The EFA resulted in a three-factor model with factors labeled General, PEM/Fatigue/Cognitive Dysfunction, and Psychological, consisting of 16, 6, and 3 items respectively (25 items in total). The reliability of the items in the EFA was .90 using a split-half reliability test. Finally, participant self-reported level of functional impairment was analyzed across the three EFA factors. Interpretations and applications to research and practice are provided.
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