有针对性的卫生监测战略。2由基因决定的对化学物质的易感性以及与健康监测有关的其他问题。

J A Indulski, Z Kowalski
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引用次数: 0

摘要

鉴于研究成果在职业卫生服务的实际活动中的应用,讨论了目前关于初级和定期体检方法的一些问题。对用于检测对特定化学因素的生化敏感性的缺陷或特性的试验的审查揭示了在一定程度上限制和延迟科学进展在健康监测中的实际应用的客观原因。讨论了有助于检测致气因子易感性的试验、动脉粥样硬化遗传标记、肿瘤(特别是膀胱肿瘤和肺癌)。根据提出的意见,进一步推进研究,以及新方法的应用,应该在较短的时间内消除现有的疑虑,实现方法的标准化。会议还讨论了目前已被引入健康监测的心理测试的有用性。研究发现,对于那些压力大、要求高可靠性的工作,测试可以大大丰富身体健康证明。它们在个人工作量评估中非常有用,并且它们允许在工作环境因素产生明显病理之前检测中枢和周围神经系统的早期疾病。在这些方法的广泛应用中,最常见的障碍包括:心理学家研究生教育不足;两个专业(劳动心理学和临床心理学)的罕见结合;缺乏在特定国家条件下经过验证的测试方法。这项工作还提出了关于电磁辐射暴露对健康的影响、复杂的有毒物质暴露、高龄工人的健康状况和定期检查等问题。
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The strategy of targetted health surveillance. II. Genetically determined susceptibility to chemical substances and other issues related to health surveillance.

A number of current issues regarding methods of primary and periodical medical examinations were discussed in view of application of research results in practical activities of the occupational health service. The review of tests employed on detection of deficiency or peculiarity of biochemical susceptibility to given chemical factors revealed objective causes limiting and delaying, to a certain extent, of practical application of scientific progress in health surveillance. Tests facilitating detection of susceptibility to emphysemagenic factors, genetic markers of atherosclerosis, neoplasm (especially neoplasm of the urinary bladder and lung cancer) were discussed. According to the opinions presented, further advancement of research, as well as application of new methods should, during a relatively short time, dispel existing doubts and accomplish standardization of methods. The usefulness of psychological tests, now being introduced to health surveillance, was also discussed. It was found that tests may enrich considerably certification of physical fitness for those jobs with high stress levels and requiring a high level of reliability. They are extremely useful in individual assessment of work load, and they allow the detection of early disorders in the central and peripheral nervous system, preceding evident pathology produced by working environment factors. The most common obstacles in the wide application of the discussed methods include: inadequate post-graduate education of psychologists; the rare combination of two specialisations (psychology of labour and clinical psychology); and a shortage of test methods which have been verified in the conditions of a given country. This work also raises questions about the health effects of exposure to electromagnetic radiation, complex exposure to toxic substances, health condition and periodical examinations in workers of advanced age.

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