{"title":"综合溶剂暴露对健康影响评估中的可加性规则——是否成立?","authors":"J A Sokal, Z Korsak","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>On the basis of results obtained in experiments on animals exposed to mixtures of solvents the adequacy of additivity rule which is used in the evaluation of health effects of combined exposure to solvents is discussed. In the case of simultaneous exposure to mixture to toluen and xylene the modification of the additivity formula is proposed.</p>","PeriodicalId":77768,"journal":{"name":"Polish journal of occupational medicine","volume":"3 3","pages":"333-6"},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The additivity rule in the evaluation of health effects of combined exposure to solvents--does it hold?\",\"authors\":\"J A Sokal, Z Korsak\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>On the basis of results obtained in experiments on animals exposed to mixtures of solvents the adequacy of additivity rule which is used in the evaluation of health effects of combined exposure to solvents is discussed. In the case of simultaneous exposure to mixture to toluen and xylene the modification of the additivity formula is proposed.</p>\",\"PeriodicalId\":77768,\"journal\":{\"name\":\"Polish journal of occupational medicine\",\"volume\":\"3 3\",\"pages\":\"333-6\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Polish journal of occupational medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polish journal of occupational medicine","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The additivity rule in the evaluation of health effects of combined exposure to solvents--does it hold?
On the basis of results obtained in experiments on animals exposed to mixtures of solvents the adequacy of additivity rule which is used in the evaluation of health effects of combined exposure to solvents is discussed. In the case of simultaneous exposure to mixture to toluen and xylene the modification of the additivity formula is proposed.
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