DNA微阵列图像处理算法的软件分析

Omar Salem Baans, A. B. Jambek
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引用次数: 2

摘要

微阵列分析是科学家关注DNA序列研究和检查基因表达最合适的工具之一。通过微阵列分析,可以获得基因表达序列,获得许多疾病的生物学信息。利用图像处理技术可以提取芯片中包含的基因表达信息。微阵列图像处理包括三个主要步骤:网格划分、分割和强度提取。本文分析了该微阵列图像处理的计算时间。结果表明,强度提取消耗了大部分的计算时间。更详细的分析表明,这种高计算时间是由于该过程的背景校正部分,如本文第二部分所讨论的。
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Software profiling analysis for DNA microarray image processing algorithm
Microarray analysis is one of the most suitable tools available for scientists concerned with DNA sequences to study and examine gene expression. Through microarray analysis, the gene expression sequence can be obtained and biological information on many diseases can be acquired. The gene expression information contained in the microarray can be extracted using image-processing techniques. Microarray image processing consists of three main steps: gridding, segmentation and intensity extraction. This paper analyses the computational time for this microarray image processing. The results show that the intensity extraction consumes majority of the overall computational time. More detail analysis reveals that this high computational time is due to the background correction part of the process, as discussed in the second part of this paper.
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