Palashakshara药品标准化

Ganapathi Rao I, Chandrakanth Halli, Subhod Kamthikar
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引用次数: 0

摘要

草药标准化是保证其质量和纯度的必要条件。Palasha (Butea monosperma)的Kshara(碱性物质)是许多阿育吠陀配方的重要成分,但其标准制造工艺(SMP)直到今天还没有尝试。本研究旨在建立帕拉沙克沙拉的SMP。在制药过程中;一般来说,在洗涤结束时获得的灰分沉积物将被丢弃。然而,在研究中,我们试图通过加水来反复洗涤沉积物,以提取更多的Kshara。帕拉沙是从当地收集并鉴定的。按照标准方法制备了Kshara,并对其进行了初步的理化分析。可以观察到,即使在连续洗涤中,灰分仍产生Kshara。第一次洗涤产生21.23% w/w Kshara,而第二次和第三次洗涤分别产生9.38%和4.76% w/w。反复洗涤产生更多的Kshara。因此,提倡反复清洗骨灰。由于研究结果令人鼓舞,类似的实验可以扩展到所有其他Kshara制剂。
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Pharmaceutical standardization of Palashakshara
Standardization of herbal drugs is essential to certify their quality and purity. Kshara (alkaline substance) of Palasha (Butea monosperma) is an important constituent in many Ayurvedic formulations, but its standard manufacturing process (SMP) is not attempted till date. This study is aimed to establish SMP for Palashakshara. In pharmaceutical process; generally, the sediments of ash obtained at the end of washes will be discarded. However, in the study, we attempted to wash the sediments repeatedly by adding water to extract more Kshara. Palasha was collected from the local area and authenticated. Kshara was prepared by following standard methods and the preliminary physicochemical profile was developed. It is observed that the ash yields Kshara even in the consecutive washes. First wash yielded 21.23% w/w Kshara, while the second and third washes yielded 9.38% w/w and 4.76% w/w, respectively. Repeated washes yield more Kshara. Hence, it is advocated to wash the ashes repeatedly. As the findings are encouraging, similar experiments can be extended to all other Kshara preparations.
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