微波骨成像:跟骨骨影及成像原型的实验评价

Bilal Amin, Colin Sheridan, Daniel Kelly, A. Shahzad, M. O’halloran, M. A. Elahi
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引用次数: 1

摘要

微波成像(MWI)可作为监测骨骼健康的替代成像方式。MWI原型的评估和表征是骨介电性能在体内研究的前驱性步骤。本文对一种新型的两层简化圆柱形3D打印人体跟骨骨模进行了实验评估,并设计了相应的骨模成像MWI原型。跟骨的形状近似于圆柱体。外层和内层分别代表皮质骨和小梁骨。每层假体填充相应的液体组织模拟混合物(TMM)。设计了一个具有六个微带天线的MWI原型,以容纳跟骨骨模。将骨模放置在成像原型中,并在每个天线处测量散射信号。此外,通过对微波测量灵敏度的测试,探讨了系统的性能。基于测量到的散射信号,我们将采用MWI算法构建介质特性图,并在今后的工作中进行交流。该双层3D打印人体跟骨骨模和成像原型可作为跟骨骨成像监测骨质疏松症临床前评估的有价值的测试平台。
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Microwave bone imaging: experimental evaluation of calcaneus bone phantom and imaging prototype
Microwave imaging (MWI) can be used as an alternate imaging modality for monitoring bone health. Evaluation and characterization of MWI prototype is a precursor step before in vivo investigation of bone dielectric properties. This paper presents experimental evaluation of a novel two layered simplified cylindrical shaped 3D printed human calcaneus bone phantom along with corresponding MWI prototype designed to image the bone phantom. The shape of the calcaneus bone was approximated with a cylinder. The external and internal layers represent cortical bone and trabecular bone respectively. Each layer of the phantom was filled with respective liquid tissue mimicking mixture (TMM). A MWI prototype was designed having six microstrip antennas in order to hold calcaneus bone phantom. The bone phantom was placed in the imaging prototype and scattered signals were measured at each antenna. Moreover, the performance of the system was explored by examining microwave measurement sensitivity. Based on the measured scattered signals the map of dielectric properties will be constructed by employing MWI algorithm and will be communicated in our future work. This two layered 3D printed human calcaneus bone phantom and imaging prototype can be used as a valuable test platform for pre-clinical assessment of calcaneus bone imaging for monitoring osteoporosis.
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