Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9384899
Hana Mozerova, R. Scapaticci, J. Vrba, L. Crocco
In this paper, we present the initial results of a research work aimed at assessing the capabilities of microwave imaging as an effective tool for in-line monitoring of regional hyperthermia treatments. Based on the variation of the electromagnetic properties of tissue due the increase of temperature, it is possible to exploit the processing of the scattered fields gathered during the thermal treatment to track its evolution. The anatomical scenario is the pelvic region and the target of the thermal treatment is the bladder. The first challenge is to verify if and to what extent microwave signals may achieve a sufficient penetration and spatial resolution to pursue the desired task. Based on a simple theoretical analysis, the suitable frequency range and operating conditions are determined and some numerical simulations involving a 2D anthropomorphic phantom are provided to show the potential of microwave imaging to undertake this monitoring task.
{"title":"Monitoring regional hyperthermia via microwave imaging: a feasibility study","authors":"Hana Mozerova, R. Scapaticci, J. Vrba, L. Crocco","doi":"10.1109/IMBIoC47321.2020.9384899","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9384899","url":null,"abstract":"In this paper, we present the initial results of a research work aimed at assessing the capabilities of microwave imaging as an effective tool for in-line monitoring of regional hyperthermia treatments. Based on the variation of the electromagnetic properties of tissue due the increase of temperature, it is possible to exploit the processing of the scattered fields gathered during the thermal treatment to track its evolution. The anatomical scenario is the pelvic region and the target of the thermal treatment is the bladder. The first challenge is to verify if and to what extent microwave signals may achieve a sufficient penetration and spatial resolution to pursue the desired task. Based on a simple theoretical analysis, the suitable frequency range and operating conditions are determined and some numerical simulations involving a 2D anthropomorphic phantom are provided to show the potential of microwave imaging to undertake this monitoring task.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130413361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9384900
A. Nefzi, R. Orlacchio, Lynn Carr, N. Lewis, Y. Percherancier, P. Lévêque, D. Arnaud-Cormos
The precise characterization of electromagnetic fields exposure systems requires accurate dosimetry from macroscale down to the cellular level. In this study, two different exposure devices based on microelectrodes arrays for real-time cellular characterization, namely a Micro-Electrode Array (MEA) and an impedancemetry well with interdigitated electrodes were considered. For the first time, the heating induced by the exposure to radiofrequency in the electrodes vicinity was retrieved from the fluorescence intensity of Rhodamine B (Rhod-B), which linearly changes as a function of the temperature variation. Our results confirm that the use of Rhod-B represents a reliable technique to obtain temperature information at the microscopic scale.
{"title":"Microscale Temperature Measurements Within Specific Exposure Systems for Real-Time Cellular Characterization","authors":"A. Nefzi, R. Orlacchio, Lynn Carr, N. Lewis, Y. Percherancier, P. Lévêque, D. Arnaud-Cormos","doi":"10.1109/IMBIoC47321.2020.9384900","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9384900","url":null,"abstract":"The precise characterization of electromagnetic fields exposure systems requires accurate dosimetry from macroscale down to the cellular level. In this study, two different exposure devices based on microelectrodes arrays for real-time cellular characterization, namely a Micro-Electrode Array (MEA) and an impedancemetry well with interdigitated electrodes were considered. For the first time, the heating induced by the exposure to radiofrequency in the electrodes vicinity was retrieved from the fluorescence intensity of Rhodamine B (Rhod-B), which linearly changes as a function of the temperature variation. Our results confirm that the use of Rhod-B represents a reliable technique to obtain temperature information at the microscopic scale.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121699639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9385044
S. Winkler, I. Saniour, Akshay Chaudhari, F. Robb, J. Vaughan
A to-date unsolved and highly limiting safety concern for Ultra High-Field (UHF) magnetic resonance imaging (MRI) is the deposition of radiofrequency (RF) power in the body, quantified by the specific absorption rate (SAR), leading to dangerous tissue heating/damage in the form of local SAR hotspots that cannot currently be measured/monitored, thereby severely limiting the applicability of the technology for clinical practice and in regulatory approval. The goal of this study has been to show proof of concept of an artificial intelligence (AI) based exam-integrated real-time MRI safety prediction software (MRSaiFE) facilitating the safe generation of 3T and 7T images by means of accurate local SAR-monitoring at sub-W/kg levels. We trained the software with a small database of image as a feasibility study and achieved successful proof of concept for both field strengths. SAR patterns were predicted with a residual root mean squared error (RSME) of < 11{%}$ along with a structural similarity (SSIM) level of > 84{%}$ for both field strengths (3T and 7T).
{"title":"MRSaiFE: Tissue Heating Prediction for MRI: a Feasibility Study","authors":"S. Winkler, I. Saniour, Akshay Chaudhari, F. Robb, J. Vaughan","doi":"10.1109/IMBIoC47321.2020.9385044","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9385044","url":null,"abstract":"A to-date unsolved and highly limiting safety concern for Ultra High-Field (UHF) magnetic resonance imaging (MRI) is the deposition of radiofrequency (RF) power in the body, quantified by the specific absorption rate (SAR), leading to dangerous tissue heating/damage in the form of local SAR hotspots that cannot currently be measured/monitored, thereby severely limiting the applicability of the technology for clinical practice and in regulatory approval. The goal of this study has been to show proof of concept of an artificial intelligence (AI) based exam-integrated real-time MRI safety prediction software (MRSaiFE) facilitating the safe generation of 3T and 7T images by means of accurate local SAR-monitoring at sub-W/kg levels. We trained the software with a small database of image as a feasibility study and achieved successful proof of concept for both field strengths. SAR patterns were predicted with a residual root mean squared error (RSME) of < 11{%}$ along with a structural similarity (SSIM) level of > 84{%}$ for both field strengths (3T and 7T).","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121791520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9384907
P. Marín, Joanatan Borges, P. Gueye, M. Vélez
In recent years, much interest and effort have been devoted to develop soft magnetic materials due to their technological potential [1]. Amorphous microwires are one of the most widely studied soft materials. They are fabricated by means of extracting melt-spinning Taylor technique. Those microwires are composed by a metallic core and a Pyrex cover both in the micrometer range. The ratio between the total diameter and the magnetic core, often called aspect ratio, is one of the key parameters of such microwires, since magnetic properties depend dramatically on it. Many properties of these materials have been deeply studied both from the point of view of the basic physics and the applications. This is the case of the giant magnetoimpedance effect [2], bistability, ferromagnetic resonance [3], and magnetoelastic resonance [4]. It is easy, also, to find much literature regarding microwave-related applications of microwires or microwire-based materials [5]. In the frequency range of GHz, some experimental and theoretical studies of the effect of the magnetization on the scattering properties of a single microwire have been developed [6]. This kind of work gives experimental evidence showing that the microwave scattering by a single microwire depends on the magnetic permeability with sufficient strength to be experimentally detected as an effect of the GMI. This dependence was used to show the potential of such microwire as a wireless field and/or stress sensor. Experimental results are followed by a theoretical approach where the influence of the microwire magnetic state in its microwave reflection features is taken into account. Besides these investigations on magnetic microwires, it should be stated that technological development has spurred the growing interest in the investigation of new biosensors aimed at simplifying present day diagnostic methods and thereby improving medical care, so that it improves the quality of life of the patients and allows for outpatient treatment for a number of pathologies, avoiding unnecessary hospital admissions. Magnetic sensors are at the helm of technological development seen in this field over the last decades, offering numerous advantages attributed to their elevated sensitivity, reduced size, systems without the need for an external source of energy, and wireless connections. The use of wireless sensor network (WSN) technologies offers the possibility of developing implantable biomedical sensors allowing for the monitorization and follow-up of certain physiological parameters with precise and, up until now, unthinkable measurements. The aim of the present work is to show the physical fundamentals and the particular biomedical applications of magnetic microwires as wireless stress sensors. Two main applications will be described. On one side we proposed a flexible magnetic element able to be integrated both in artery and prosthesis suitable for wireless localized blood pressure monitoring. The sensor made of a
{"title":"Wireless Stress Sensor Based on Magnetoelastic Microwires for Biomedical Applications: detection of collagen concentration","authors":"P. Marín, Joanatan Borges, P. Gueye, M. Vélez","doi":"10.1109/IMBIoC47321.2020.9384907","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9384907","url":null,"abstract":"In recent years, much interest and effort have been devoted to develop soft magnetic materials due to their technological potential [1]. Amorphous microwires are one of the most widely studied soft materials. They are fabricated by means of extracting melt-spinning Taylor technique. Those microwires are composed by a metallic core and a Pyrex cover both in the micrometer range. The ratio between the total diameter and the magnetic core, often called aspect ratio, is one of the key parameters of such microwires, since magnetic properties depend dramatically on it. Many properties of these materials have been deeply studied both from the point of view of the basic physics and the applications. This is the case of the giant magnetoimpedance effect [2], bistability, ferromagnetic resonance [3], and magnetoelastic resonance [4]. It is easy, also, to find much literature regarding microwave-related applications of microwires or microwire-based materials [5]. In the frequency range of GHz, some experimental and theoretical studies of the effect of the magnetization on the scattering properties of a single microwire have been developed [6]. This kind of work gives experimental evidence showing that the microwave scattering by a single microwire depends on the magnetic permeability with sufficient strength to be experimentally detected as an effect of the GMI. This dependence was used to show the potential of such microwire as a wireless field and/or stress sensor. Experimental results are followed by a theoretical approach where the influence of the microwire magnetic state in its microwave reflection features is taken into account. Besides these investigations on magnetic microwires, it should be stated that technological development has spurred the growing interest in the investigation of new biosensors aimed at simplifying present day diagnostic methods and thereby improving medical care, so that it improves the quality of life of the patients and allows for outpatient treatment for a number of pathologies, avoiding unnecessary hospital admissions. Magnetic sensors are at the helm of technological development seen in this field over the last decades, offering numerous advantages attributed to their elevated sensitivity, reduced size, systems without the need for an external source of energy, and wireless connections. The use of wireless sensor network (WSN) technologies offers the possibility of developing implantable biomedical sensors allowing for the monitorization and follow-up of certain physiological parameters with precise and, up until now, unthinkable measurements. The aim of the present work is to show the physical fundamentals and the particular biomedical applications of magnetic microwires as wireless stress sensors. Two main applications will be described. On one side we proposed a flexible magnetic element able to be integrated both in artery and prosthesis suitable for wireless localized blood pressure monitoring. The sensor made of a ","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129830921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9385054
Javad Ebrahimizadeh, Alireza Maananejad, S. Sadeghi, R. Karlsson, Bappaditya Mandal, P. Rangaiah, M. Pérez, R. Augustine
This paper presents the feasibility of using a microwave imaging system for monitoring bone mineralization progress overtime after craniotomy surgery. Any variation in the composition of the bone flap can be monitored as a variation in the intensity of the image. A simulation is conducted on a head structure derived from a numerical head phantom based on anatomically realistic MRI–derived FDTD models using commercial CST 2019 software. For simulation, a defect is provided in the skull layer surrounded by a 9–elements antenna. Applying Space-Frequency Time Reversal (TR) method, the image of defect is constructed for different permittivity of the defect ranging from 16 to 36. Results show that the image intensity at the defect location will decrease as the permittivity of the defect decreases.
{"title":"Time Reversal Microwave Imaging of Realistic Numerical Head Phantom for Bone Flap Healing Follow-up","authors":"Javad Ebrahimizadeh, Alireza Maananejad, S. Sadeghi, R. Karlsson, Bappaditya Mandal, P. Rangaiah, M. Pérez, R. Augustine","doi":"10.1109/IMBIoC47321.2020.9385054","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9385054","url":null,"abstract":"This paper presents the feasibility of using a microwave imaging system for monitoring bone mineralization progress overtime after craniotomy surgery. Any variation in the composition of the bone flap can be monitored as a variation in the intensity of the image. A simulation is conducted on a head structure derived from a numerical head phantom based on anatomically realistic MRI–derived FDTD models using commercial CST 2019 software. For simulation, a defect is provided in the skull layer surrounded by a 9–elements antenna. Applying Space-Frequency Time Reversal (TR) method, the image of defect is constructed for different permittivity of the defect ranging from 16 to 36. Results show that the image intensity at the defect location will decrease as the permittivity of the defect decreases.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127910086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9385028
F. Snigdha, S. M. Islam, O. Boric-Lubecke, V. Lubecke
In-home sleep monitoring system using Microwave Doppler radar is gaining attention as it is unobtrusive and noncontact form of measurement. Most of the reported results in literature focused on utilizing radar-reflected signal amplitude to recognize Obstructive sleep apnea (OSA) events which requires iterative analysis and cannot recommend about sleep positions also (supine, prone and side). In this paper, we propose a new, robust and automated ERCS-based (Effective Radar Cross section) method for classifying OSA events (normal, apnea and hypopnea) by integrating radar system in a clinical setup. In our prior attempt, ERCS has been proven versatile method to recognize different sleep postures. We also employed two different machine learning classifiers (K-nearest neighbor (KNN) and Support Vector machine (SVM) to recognize OSA events from radar captured ERCS and breathing rate measurement from five different patients' clinical study. SVM with quadratic kernel outperformed with other classifiers with an accuracy of 96.7 % for recognizing different OSA events. The proposed system has several potential applications in healthcare, continuous monitoring and security/surveillance applications.
{"title":"Obstructive Sleep Apnea (OSA) Events Classification by Effective Radar Cross Section (ERCS) Method Using Microwave Doppler Radar and Machine Learning Classifier","authors":"F. Snigdha, S. M. Islam, O. Boric-Lubecke, V. Lubecke","doi":"10.1109/IMBIoC47321.2020.9385028","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9385028","url":null,"abstract":"In-home sleep monitoring system using Microwave Doppler radar is gaining attention as it is unobtrusive and noncontact form of measurement. Most of the reported results in literature focused on utilizing radar-reflected signal amplitude to recognize Obstructive sleep apnea (OSA) events which requires iterative analysis and cannot recommend about sleep positions also (supine, prone and side). In this paper, we propose a new, robust and automated ERCS-based (Effective Radar Cross section) method for classifying OSA events (normal, apnea and hypopnea) by integrating radar system in a clinical setup. In our prior attempt, ERCS has been proven versatile method to recognize different sleep postures. We also employed two different machine learning classifiers (K-nearest neighbor (KNN) and Support Vector machine (SVM) to recognize OSA events from radar captured ERCS and breathing rate measurement from five different patients' clinical study. SVM with quadratic kernel outperformed with other classifiers with an accuracy of 96.7 % for recognizing different OSA events. The proposed system has several potential applications in healthcare, continuous monitoring and security/surveillance applications.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134281652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9385019
Lena Kranold, Muberra Ozmen, M. Coates, M. Popovic
We here report on a protocol of system performance for the microwave radar breast health monitoring prototype. The device aims to detect breast cancer at an early stage and operates in the multistatic mode with 16 transceiving antennas. After introducing hardware changes, we developed a system performance protocol to repeatably test our system in preparation for clinical trials. It includes repeated scans using breast phantoms, and we investigated if the phantoms can be used without a matching medium not only with an ideally-fitting antenna housing, but also with the prosthetic bra used in clinical trials. We compare the system performance with both antenna housing options and introduce a system performance protocol for the clinical trials.
{"title":"Microwave Radar for Breast Health Monitoring: System Performance Protocol","authors":"Lena Kranold, Muberra Ozmen, M. Coates, M. Popovic","doi":"10.1109/IMBIoC47321.2020.9385019","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9385019","url":null,"abstract":"We here report on a protocol of system performance for the microwave radar breast health monitoring prototype. The device aims to detect breast cancer at an early stage and operates in the multistatic mode with 16 transceiving antennas. After introducing hardware changes, we developed a system performance protocol to repeatably test our system in preparation for clinical trials. It includes repeated scans using breast phantoms, and we investigated if the phantoms can be used without a matching medium not only with an ideally-fitting antenna housing, but also with the prosthetic bra used in clinical trials. We compare the system performance with both antenna housing options and introduce a system performance protocol for the clinical trials.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124420036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9385043
Mario Mueh, P. Hinz, C. Damm
A complementary approach to the fabrication of microfluidic systems is presented with the aim of reducing attenuation of resonator-based sensors in proximity of aqueous media. Contrary to state-of-the-art techniques, the channel system is dry-etched into a PET film, which also carries a functional RF metalization forming an array of split-ring resonators. This technique is easy to implement in standard micro-lithography and provides high flexibility in placement of the electrodes. Verified process parameters for etching depths up to $boldsymbol{13.5mu mathrm{m}}$. are presented together with a functional concept validation, comparing fullwave simulation results to a prototype device.
{"title":"Single-substrate Microfluidic Systems on PET Film for mm-Wave Sensors","authors":"Mario Mueh, P. Hinz, C. Damm","doi":"10.1109/IMBIoC47321.2020.9385043","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9385043","url":null,"abstract":"A complementary approach to the fabrication of microfluidic systems is presented with the aim of reducing attenuation of resonator-based sensors in proximity of aqueous media. Contrary to state-of-the-art techniques, the channel system is dry-etched into a PET film, which also carries a functional RF metalization forming an array of split-ring resonators. This technique is easy to implement in standard micro-lithography and provides high flexibility in placement of the electrodes. Verified process parameters for etching depths up to $boldsymbol{13.5mu mathrm{m}}$. are presented together with a functional concept validation, comparing fullwave simulation results to a prototype device.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133645146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-14DOI: 10.1109/IMBIoC47321.2020.9385055
Bilal Amin, Colin Sheridan, Daniel Kelly, A. Shahzad, M. O’halloran, M. A. Elahi
Microwave imaging (MWI) can be used as an alternate imaging modality for monitoring bone health. Evaluation and characterization of MWI prototype is a precursor step before in vivo investigation of bone dielectric properties. This paper presents experimental evaluation of a novel two layered simplified cylindrical shaped 3D printed human calcaneus bone phantom along with corresponding MWI prototype designed to image the bone phantom. The shape of the calcaneus bone was approximated with a cylinder. The external and internal layers represent cortical bone and trabecular bone respectively. Each layer of the phantom was filled with respective liquid tissue mimicking mixture (TMM). A MWI prototype was designed having six microstrip antennas in order to hold calcaneus bone phantom. The bone phantom was placed in the imaging prototype and scattered signals were measured at each antenna. Moreover, the performance of the system was explored by examining microwave measurement sensitivity. Based on the measured scattered signals the map of dielectric properties will be constructed by employing MWI algorithm and will be communicated in our future work. This two layered 3D printed human calcaneus bone phantom and imaging prototype can be used as a valuable test platform for pre-clinical assessment of calcaneus bone imaging for monitoring osteoporosis.
{"title":"Microwave bone imaging: experimental evaluation of calcaneus bone phantom and imaging prototype","authors":"Bilal Amin, Colin Sheridan, Daniel Kelly, A. Shahzad, M. O’halloran, M. A. Elahi","doi":"10.1109/IMBIoC47321.2020.9385055","DOIUrl":"https://doi.org/10.1109/IMBIoC47321.2020.9385055","url":null,"abstract":"Microwave imaging (MWI) can be used as an alternate imaging modality for monitoring bone health. Evaluation and characterization of MWI prototype is a precursor step before in vivo investigation of bone dielectric properties. This paper presents experimental evaluation of a novel two layered simplified cylindrical shaped 3D printed human calcaneus bone phantom along with corresponding MWI prototype designed to image the bone phantom. The shape of the calcaneus bone was approximated with a cylinder. The external and internal layers represent cortical bone and trabecular bone respectively. Each layer of the phantom was filled with respective liquid tissue mimicking mixture (TMM). A MWI prototype was designed having six microstrip antennas in order to hold calcaneus bone phantom. The bone phantom was placed in the imaging prototype and scattered signals were measured at each antenna. Moreover, the performance of the system was explored by examining microwave measurement sensitivity. Based on the measured scattered signals the map of dielectric properties will be constructed by employing MWI algorithm and will be communicated in our future work. This two layered 3D printed human calcaneus bone phantom and imaging prototype can be used as a valuable test platform for pre-clinical assessment of calcaneus bone imaging for monitoring osteoporosis.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133039619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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