中东和非洲医生对多囊卵巢综合征的诊断和治疗

S. Atkin
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摘要

多囊卵巢综合征(PCOS)是育龄妇女最常见的内分泌疾病,可能会出现在内分泌学家、妇科医生、皮肤科医生甚至精神科医生那里。1 .经济医疗负担是相当大的,仅在美国就估计为46亿美元;然而,月经不规律、不孕症、多毛症、肥胖和生活质量下降等相关疾病对多囊卵巢综合征患者有重大影响,并有可能发展为糖尿病、子宫内膜癌和心血管疾病。1,2多囊卵巢综合征是在应用鹿特丹标准、雄激素过量社会指南或国家卫生研究所共识的诊断标准之前,排除其他疾病如高催乳素血症、先天性肾上腺增生和甲状腺功能障碍的诊断。已经有几篇文章给出了国际基于证据的PCOS评估和管理指南的建议。《糖尿病与内分泌实践杂志》(Journal of Diabetes and Endocrine Practice, JDEP)上发表了一项关于中东和非洲医生对糖尿病并发症管理的调查。问题是中东和非洲的医生如何反映已公布的指导方针?从报告来看,总体反应率尚不清楚,但总共有190名反应者可供分析。有报道称,这可能会影响到整个实践,因此没有妇产科医生对此作出回应。此外,资源的可用性可能对响应中心的实践产生重大影响。总的来说,它
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Diagnosis and Management of Polycystic Ovary Syndrome by Physicians from the Middle East and Africa
Polycystic ovary syndrome (PCOS) is the most common endocrine disease in women of reproductive age that may present to endocrinologists, gynecologists, dermatologists, or even the psychiatric services. 1 The economic healthcare burden is considerable and estimated at $4.6 billion in the United States alone; however, the associated disorders of menstrual irregularity, infertility, hirsutism, obesity, and impaired quality of life have a major impact on those with PCOS, and havethe potential for the developmentofdiabetes, endometrial cancer, and cardiovascular disease. 1,2 PCOS is a diagnosis of exclusion of other conditions such as hyper-prolactinemia, congenital adrenal hyperplasia, and thyroid dysfunction before the application of the diagnostic criteria reported for the Rotterdam criteria, androgen excess society guidelines, or the National Institute of Health consensus. 3 There have been several articles that have given recommendations from international evidence-based guidelines for the assessment and management of PCOS. 4 A survey of man-agementofPCOSbyphysiciansfromtheMiddleEastandAfrica is published in the current issue of Journal of Diabetes and Endocrine Practice (JDEP). 5 The question is how does physicians within the Middle East and Africa re fl ect published guidelines? From the report, the overall response rate was unclear, but 190 responders in total were available for analy-sis. 5 Therewasabiasforendocrinologists torespond,thatmay have affected the overall practice, that was reported. In addi-tion, the availability of resources may have had a major effect onthepracticeineachofthecentersthatresponded.Overall,it
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