COVID-19感染患者d -二聚体值的评估

R. Pervaiz, B. Arif, K. Tehreem, N. Gull, A. Munawar, S. Raza, M. Sufiyan
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摘要

新冠肺炎疫情引发的全球灾难对健康和经济都产生了负面影响。凝血系统可能参与了COVID-19的病理生理,因为d -二聚体(一种高凝性指标)在COVID-19重症患者中更高。为了确定d -二聚体水平与疾病严重程度之间是否存在关系,本研究测量了COVID-19重症和非重症患者的d -二聚体水平。研究对象中72例新冠肺炎确诊患者的平均年龄为52.85 ~ 10.65岁。根据严重程度,将个体分为两组,并测量每组中d -二聚体的水平。根据这项研究,与症状不太严重的个体相比,COVID-19症状严重的患者的d -二聚体水平要高得多。咳嗽、发烧、呼吸困难和胃肠道症状在症状严重的患者中也有统计学意义。个体中最普遍的合并症是高血压和糖尿病。这些结果强调了识别有不良预后风险的患者、跟踪他们的d -二聚体水平的重要性,并表明d -二聚体水平可能是COVID-19患者的一个有用的预后指标。
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ASSESSMENT OF D. DIMER VALUE IN COVID-19 INFECTED PATIENTS
A global catastrophe caused by the COVID-19 epidemic has had negative effects on both health and the economy. The coagulation system may be involved in the pathophysiology of COVID-19 since D-Dimer, a measure of hypercoagulability, is higher in COVID-19 individuals with severe illness. In order to determine whether there is a relationship between D-Dimer levels and disease severity, this study measured the levels of D-Dimer in COVID-19 patients with severe and non-severe disease. The average age of the 72 confirmed COVID-19 patients in the research was 52.85 10.65. Based on the severity, the individuals were split into two groups, and the levels of D-Dimer were measured in each group. In contrast to individuals with less severe symptoms, those with severe COVID-19 symptoms had considerably higher levels of D-Dimer, according to the study. Cough, fever, breathing difficulties, and gastrointestinal symptoms were also discovered in the study to be statistically significant in patients with severe symptoms. The most prevalent co-morbid conditions among the individuals were hypertension and diabetes. These results emphasise the significance of identifying patients at risk for poor outcomes, tracking their D-Dimer levels and suggesting that D-Dimer levels may be a helpful prognostic marker in COVID-19 patients.
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