冠状动脉支架的参数化设计与有限元模拟

S. Tayyebi, Sara Ghasemi, M. Mokhlesabadi, S. Barati, N. Fatouraee
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引用次数: 0

摘要

心血管疾病的高患病率增加了使用不同支架的需求。为了防止支架再狭窄,设计和制造更安全的冠状动脉血管成形术支架是必不可少的。然而,新支架设计的原型和机械测试是具有挑战性的,耗时且昂贵的过程。因此,参数化模型和有限元模拟可以帮助设计人员改进支架设计。在本研究中,三个市售的冠状动脉支架根据其直径、环数、峰值数和支撑厚度进行参数化设计和建模。此外,对每个模型在动脉中的扩张进行了有限元模拟,以研究链接对支架功能和血管损伤的影响。结果表明,支架在冠状动脉内放置过程中的外加应力超出弹性极限,支架材料进入塑性区。施加的应变小于材料的破坏应变。通过比较不同类型支架的最大Von-Mises应力、预缩和狗骨化,可以得出闭细胞支架是一种更安全的模型,对血管损伤的副作用更小。然而,开放细胞支架提供了更多的灵活性,在弯曲的血管中是有利的。值得注意的是,支架的参数化建模有助于今后支架的研究和有限元分析,了解几何参数对支架功能的影响。
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Parametric Design and Finite Element Simulation of Coronary Stents
The high prevalence of cardiovascular diseases has increased the demand for using different stents. To prevent instent restenosis, the design and fabrication of safer stents for coronary angioplasty is essential. However, prototyping and mechanical testing of new stent designs are challenging, time-consuming, and expensive procedures. Therefore, parametric models and finite element simulations are used to help designers improve stent designs. In this study, three commercially available coronary stents are parametrically designed and modeled based on their diameter, number of rings, number of peaks, and strut thickness. Moreover, a finite element simulation of the expansion of each model in the artery is performed to investigate the effect of links on stent function and vascular injury. The results demonstrate that the applied stresses on the stent during its placement in the coronary artery are beyond elastic limits, and the stent’s material enters its plastic zone accordingly. The applied strain is less than the failure strain of the material. By comparing maximum Von-Mises stress, foreshortening, and dogboning of different types of stents, it can be concluded that the closed-cell stent is a safer model and causes fewer side effects regarding vascular injuries. However, open-cell stents provide more flexibility and can be advantageous in curved vessels. It is noteworthy that parametric modeling of stents can be beneficial in future studies and finite element analysis of stents for understanding the effect of the geometric parameters on stent function.
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