基因疗法如何用于治疗临床抑郁症患者?

Joshua Joh
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摘要

临床抑郁症可以被描述为一种常见的医学疾病,它会对个人的感觉、思考和行为产生负面影响。今天,一个人患抑郁症的几率在世界范围内更为普遍,了解抑郁症是至关重要的,最重要的是如何治疗这种疾病。虽然目前还不清楚抑郁症是如何在人体中起作用的,但研究表明,一种名为P11的蛋白质可能在体内抑郁症的分子和细胞机制中起着至关重要的作用。根据研究,随着P11蛋白水平的降低,个体患抑郁症的风险会增加。主要的问题是,现有的治疗方法,包括药物和心理治疗,并没有达到治疗这种疾病的效果。基因疗法是治疗抑郁症的一种有吸引力的替代疗法,因为调节P11蛋白的水平和机制有望减轻体内抑郁症的症状。本文旨在强调使用基因疗法治疗抑郁症的好处,并详细说明为什么这种疗法可能是有用的。
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How genetic therapy can be used to treat patients undergoing clinical depression?
Clinical depression can be described as a common medical disorder that negatively affects how an individual feels, thinks, and acts. Today, the chances of a person suffering from depression are much more common worldwide, and it is critical to understand depression and most importantly how to treat the disease. While it currently remains unclear exactly how depression works in the human body, research shows that a protein called P11 might play a vital role in the molecular and cellular mechanisms underlying depression in the body. According to research, as the level of P11 protein decreases, it increases an individual’s risk of undergoing depression. The main problem is that the existing treatment, which includes medication and psychotherapy, is not as effective as it could be for treating such a disease. Genetic therapy treatment would be an attractive alternative treatment for depression treatment since regulating the levels and mechanisms involving protein P11 would hopefully alleviate one’s symptoms of depression in the body. This paper intends to highlight the benefits of using gene therapy to treat depression and elaborate on why the treatment may be useful.
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