使用无线神经传感系统记录神经尖峰

Carolina Moncion, I. S. B. Venkatakrishnan, A. Kiourti, J. R. Diaz, J. Volakis
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引用次数: 0

摘要

提出并验证了一种基于阻抗匹配网络的无线神经传感系统。该系统首次在体内记录了Wistar大鼠海马的自发神经单元活动。这些细胞外突起提供了有价值的信息。然而,观察它们具有挑战性,由于与所需神经探针的阻抗不匹配,先前报道的神经传感系统更是如此。本文所展示的显著结果采用了(a)最近提出的无源阻抗匹配技术,以及(b)新探索的降低阻抗的电化学探针涂层方法。提出的技术在神经学研究,特别是癫痫研究中具有革命性的潜力。
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Recording Neural Spikes Using Wireless Neurosensing System
A wireless neurosensing system (WiNS) adapted with a novel impedance matching network is presented and validated. This system is used in vivo to record for the first time spontaneous neural unit activity from the hippocampus of a Wistar rat. These extracellular spikes offer valuable information. However, they are challenging to observe, even more so with previously reported neurosensing systems due to impedance mismatches with the required neural probes. The notable result demonstrated here employed (a) recently proposed technique for passive impedance matching, and (b) newly explored impedance reducing electrochemical probe coating method. The proposed technology has revolutionary potential in neurological research, particularly in epilepsy studies.
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