低冲击饮酒引起的呼吸酒精浓度波动和认知能力下降的研究

Yuichi Sato, Kosuke Nagano, Fumiya Kinoshita, Hideaki Touyama
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摘要

在日本,《道路交通法》(Road Traffic Law)禁止酒后驾驶,规定呼气酒精浓度为0.15毫克/升时处罚。然而,即使在呼气酒精浓度低于标准值的情况下,每年仍有300起酒驾事件发生。这表明,即使少量饮酒也可能导致大脑功能下降。在这项研究中,我们使用事件相关电位(EEG)来评估低强度饮酒引起的脑功能。结果显示,与饮酒前相比,饮酒后10、30、50分钟呼气酒精浓度显著升高(p < 0.05)。事件相关电位在这些时间段内也发生了显著变化(p < 0.05)。另一方面,在饮酒后的前70分钟,呼气酒精浓度没有显著差异,但事件相关电位有显著变化。目前的研究表明,低负荷下的低酒精摄入量会导致大脑功能下降。
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A Study of Breath Alcohol Concentration Fluctuations and Cognitive Decline Due to Low-Impact Drinking
In Japan, drunk driving is prohibited under the Road Traffic Law, and penalties are set at a breath alcohol concentration of 0.15 mg/l. However, 300 cases of drunk driving occur annually even when the breath alcohol concentration is below the standard value. This suggests that even small amounts of alcohol consumption may cause a decline in brain function. In this study, we evaluated the brain function caused by low-intensity drinking using event-related potentials, a type of electroencephalogram (EEG). The results showed that breath alcohol concentration increased significantly (p < 0.05) at 10, 30, and 50 minutes after drinking compared to before drinking. Event-related potentials during these time periods also changed significantly (p < 0.05). On the other hand, there was no significant difference in expiratory alcohol concentration during the first 70 minutes after drinking, but there was a significant change in event-related potentials. The present study suggests that low alcohol intake at low loads causes a decrease in brain function.
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