多步骤有机合成导致形成三嗪噻唑喹啉,涉及成本有效的试剂

Amar Yadav, V. K. Pandey
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引用次数: 0

摘要

在常温下,利用草酸、pcl5硫脲、芳香醛和硫氰酸铵等易得且成本较低的试剂,通过邻苯二胺的环化反应,尝试了一种简单有效的化学方法,以中等至优异的产率合成具有重要生物学和商业意义的2-芳基[-s-]三氮基[1]、[3]、[5]噻唑[6]、[5-b]喹诺啉-4-硫酮。
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Multistep organic synthesis leading to the formation of triazinothiazoloquinoxalines involving cost effective rea-gents
A simple and efficient chemical method has been attempted for the synthesis of biologically and commercially important 2-aryl [-s-] triazino [1], [3], [5] thiazolo [6], [5-b] quinoxalin -4- thiones in moderate to excellent yields through cyclization reaction of o-phenylenediamino using readily available and fewer costly reagents viz. oxalic acid, PCl5thiourea, aromatic aldehydes and ammonium thiocyanate at an ambient temperature.
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