Acute Clostridium Difficile Infection in two Polish Pregnant Women with Premature Rupture of Membranes

We present two cases of acute Clostridium difficile infection (CDI) during pregnancy in Poland. Both patients were hospitalized due to premature rupture of membranes at 15 and 28 weeks of gestation and had antibiotic prophylaxy and therapy. The first patient was discharged on day 18 after the start of the infection but the second patient died after 4 days of hospitalization. Our data and a literature review show that extensive antibiotic usage in such patients may predispose to CDI despite a current lack of detailed studies.BV and health state will provide the depth insight in the etiology of BV.