三阴性浸润性导管细胞癌的治疗

Z. Ahsan, A. Salman, T. Todd
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摘要

我们报告了一个三阴性乳腺癌的病例谁提出了在我们的医疗中心在左乳房的上外象限肿块。患者就诊时年龄为74岁零8个月。乳腺超声示左乳上外象限一3.3 cm × 2.7 cm分叶状低回声纤维腺肿块。左乳浸润性导管细胞癌三阴性(雌激素受体/孕激素受体/人表皮生长因子受体2/新阴性),浸润皮肤,未固定胸壁。新辅助化疗使肿瘤体积减小至2.1 cm × 1.2 cm。然后行部分乳房切除术,部分腋窝清扫和辅助放疗。在1年的随访中,乳房x光检查和超声检查均未发现肿瘤复发或近期肿块,表明乳腺三阴性肿瘤治疗成功。我们的结论是,三阴性乳腺肿瘤应采用新辅助化疗,如紫杉烷和顺铂,然后进行辅助放疗。
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Management of triple-negative invasive ductal cell carcinoma
We reported a case of triple-negative breast cancer who presented to our medical center with a mass in the upper outer quadrant of the left breast. The age of the patient at the time of presentation was 74 years and 8 months. Breast ultrasound revealed a 3.3 cm × 2.7 cm lobulated hypoechoic fibroglandular mass in the upper outer quadrant of the left breast. Core biopsy showed triple-negative (estrogen receptor/progesterone receptor/human epidermal growth factor receptor 2/neu negative) invasive ductal cell cancer of the left breast infiltrating into the skin but no fixation to the chest wall. Neoadjuvant chemotherapy reduced the size of the mass to 2.1 cm × 1.2 cm. Partial mastectomy was then performed along with partial axillary dissection and adjuvant radiotherapy. No recurrence of tumor or any recent breast mass was noted at 1-year follow-up on both mammography and ultrasonography, indicating successful management of triple-negative breast tumor. We conclude that triple-negative breast tumors should be managed with neoadjuvant chemotherapy such as taxanes and cisplatins followed by adjuvant radiotherapy.
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