急性尼卡地平和硝苯地平中毒。多中心研究。法国中毒控制中心和ARIT的合作研究。

J M Droy, E Daridon, J Leroy, P Massari
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引用次数: 0

摘要

一项由法国中毒控制中心协会完成的研究,试图评估二氢吡啶衍生物对人体的毒性,并与其他据说毒性更大的钙拮抗剂进行比较。虽然,考虑到二氢吡啶衍生物对心脏的影响罕见或缺乏,它们的毒性远没有那么重要,但在大量摄入的情况下,或者与精神药物或心药同时服用的情况下,它绝不能被低估。
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[Acute nicardipine and nifedipine poisoning. Multicenter study. Cooperative study by the french poison control centers and the ARIT].

A study, that was realized by the French Association of Poison Control Centers, tried to estimate the toxicity of Dihydropyridine derivatives towards human beings, in comparison with other calcium antagonists, said to be more toxic. Though, the toxicity of the Dihydropyridine derivatives happens to be far less important considering the rarity or absence of their cardiac effects, it must not however be underestimated in the case of a mass ingestion, or if they are taken simultaneously with psychotropic or cardiotropic drugs.

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