接触史和家庭收入对北苏门答腊巴东斯丁普安地区肺结核发病风险的影响

Fazidah Aguslina, Wirsal Hasan
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摘要

背景:结核病(TB)仍然是世界上最致命的传染病之一。2016年,1040万人罹患结核病,170万人死于该病(包括40万艾滋病毒感染者)。95%以上的结核病死亡发生在低收入和中等收入国家。七个国家占总数的64%,其中印度居首,其次是印度尼西亚、中国、菲律宾、巴基斯坦、尼日利亚和南非。鉴于大多数结核病死亡是可以预防的,但该疾病的死亡人数仍然高得令人无法接受,因此必须加快防治结核病的努力。本研究旨在了解北苏门答腊巴东斯丁普安地区接触史和家庭收入对肺结核发病风险的影响。研究对象和方法:本研究是在北苏门答腊Padangsidimpuan的几个Puskesmas(社区卫生中心)进行的病例对照研究。本研究共选取90例患者,其中45例为结核病例,45例为对照。因变量为肺结核。自变量为接触史和家庭收入。采用抗酸结核(AFT)杆菌试验检测肺结核病例。其他数据采用问卷调查的方式收集。数据采用多元逻辑回归分析。结果:有结核接触史者患肺结核的风险增高(OR= 4,01;95% CI= 1.67 ~ 9.66;p= 0.002),家庭收入低(OR= 2.53;95% CI= 1.07 ~ 5.9;p = 0.033)。结论:有结核病接触史和家庭收入低的人群患肺结核的风险增加。
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Effects of Contact History and Family Income on the Risk of Pulmonary Tuberculosis in Padangsidimpuan, North Sumatera
Background: Tuberculosis (TB) remains one of the world’s deadliest communicable diseases. In 2016, 10.4 million people fell ill with TB, and 1.7 million died from the disease (including 0.4 million among people with HIV). Over 95% of TB deaths occur in low and middle-income countries. Seven countries account for 64% of the total, with India leading the count, followed by Indonesia, China, Philippines, Pakistan, Nigeria, and South Africa. Given that most deaths from TB are preventable, the death toll from the disease is still unacceptably high and efforts to combat it must be accelerated. This study aimed to determine the effects of contact history and family income on the risk of pulmonary TB in Padangsidimpuan, North Sumatera. Subejcts and Method: This was a case control study conducted at several Puskesmas (Community Health Center) in Padangsidimpuan, North Sumatera. A total of 90 patients consisting of 45 TB cases and 45 controls were selected for this study. The dependent variable was pulmonary TB. The independent variables were contact history and family income. Pulmonary TB cases were determined by sputum acid fast tuberculosis (AFT) bacilli test. The other data were collected by questionnaire. The data were analyzed by a multiple logistic regression. Results: The risk of pulmonary TB increased with history of TB contact (OR= 4,01; 95% CI= 1.67 to 9.66; p= 0.002) and low family income (OR= 2.53; 95% CI= 1.07 to 5.9; p= 0.033). Conclusion: The risk of pulmonary TB increases with history of TB contact and low family income.
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