胶原蛋白和明胶

B. Brodsky, J. Werkmeister, J. Ramshaw
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引用次数: 14

摘要

引言历史概述早期背景胶原蛋白发现的黄金时代组成,构象,和纤维组织氨基酸序列,遗传多样性,化学结构异常氨基酸特征及翻译后修饰胶原链交联胶原蛋白三螺旋结构胶原蛋白发生与功能成纤维胶原蛋白非纤维胶原蛋白生物合成与生物化学胶原蛋白生理生物降解多肽模型胶原蛋白分子遗传学及胶原疾病化学分析与检测生产与应用胶原蛋白生物医学应用明胶的生产和应用重组胶原蛋白和明胶对胶原蛋白产品的免疫反应专利展望明胶;三重螺旋;纤维蛋白;细胞外基质;羟脯氨酸;羟赖氨酸;交叉连接;基质金属蛋白酶;成骨不全症;肽模型;prolyl羟化酶;重组;生物材料;免疫学;胶原;顺反异构化;胶原蛋白的专利;明胶的专利;肌腱;多肽;皮革;重组胶原蛋白;氢键;伴侣;水化;亚氨基的酸
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Collagens and Gelatins
Introduction Historical Outline Early Background The Golden Age of Collagen Discoveries: Composition, Conformation, and Fibril Organization Amino Acid Sequence, Genetic Diversity, and Precursors Chemical Structure Unusual Amino Acid Features and Post-translational Modifications Cross-links Between Collagen Chains Structure of the Collagen Triple Helix Occurrence and Function of Collagen Fibril-forming Collagens Non-fibrillar Collagens Biosynthesis and Biochemistry of Collagen Physiology Biodegradation Polypeptide Models of Collagen Molecular Genetics and Collagen Diseases Chemical Analysis and Detection Production and Applications Biomedical Applications of Collagen Gelatin Production and Applications Recombinant Collagen and Gelatin Immunological Response to Collagen Products Patents Outlook and Perspectives Acknowledgements Keywords: collagen; gelatin; triple helix; fibrous proteins; extracellular matrix; hydroxyproline; hydroxylysine; cross-links; matrix metalloproteinases; osteogenesis imperfecta; peptide models; prolyl hydroxylase; recombinant; biomaterials; immunology; procollagen; cis-trans isomerization; collagen patents; gelatin patents; tendon; polypeptides; leather; recombinant collagens; hydrogen bonding; chaperone; hydration; imino acids
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