在收集异体外周血干细胞时，门诊给予粒细胞集落刺激因子的安全性和有效性:86名供者10年的单中心经验

Journal of Hematopoietic Cell Transplantation Pub Date : 2021-05-10 DOI:10.7889/HCT-20-022

Koichi Osaki, Satoshi Morishige, Takayuki Nakamura, Y. Takagi, Yoshitaka Yamasaki, Shuki Oya, Maki Yamaguchi, Koichi Egashira, Takuro Imai, Takuma Hazama, K. Murotani, K. Aoyama, Fumihiko Mouri, K. Nagafuji

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摘要

将从骨髓中动员的造血干细胞收集到健康供者的血液中，现在已成为世界各地的常规程序，与骨髓收集相比，其毒性至少相当或更安全。在收集异体外周血干细胞时，以门诊为基础给予粒细胞集落刺激因子的安全性和有效性:86名供者10年的单中心经验

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The collection of hematopoietic stem cells mobilized from the bone marrow into the bloodstream of healthy donors has now become a routine procedure throughout the world, with at least comparable or safer toxic profile compared to bone marrow collection. For the mobilization of peripheral blood stem cells(PBSC), administration of granulocyte colonySafety and efficacy of outpatient-based administration of granulocyte colony-stimulating factor in collection of allogeneic peripheral blood stem cells: 10 years of single-center experience in 86 donors

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Journal of Hematopoietic Cell Transplantation

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