鉴定几种可能用作抗疟疾的竹叶的生物活性化合物

Agus Sujarwanta, Suharno Zen
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Phytochemical screening aims to isolate bioactive compounds from bamboo based on their traditional use or local wisdom. This research was carried out at the PMIPA Biology laboratory, Muhammadiyah Metro University, Metro City, Lampung Province from January 2022 to June 2022. This type of research is descriptive qualitative. Parameters observed were color and content of bioactive compounds in the quantitative test of flavonoids and alkaloids, qualitative tests of flavonoids, alkaloids, saponins and tannins. The test was carried out for 1 time of replication. Primary data in the form of observation and documentation activities. Observations in the form of phytochemical screening to distinguish the content of secondary metabolites in the form of quantitative tests of flavonoids and alkaloids, qualitative tests of flavonoids, alkaloids, saponins and tannins. The results obtained phytochemicals from 3 types of bamboo leaves, namely flavonoid compounds, alkaloids, saponins, and tannins. 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引用次数: 0

摘要

竹子有药用的潜力。根据Agus & Zen(2020)关于鉴定竹(Bambusa sp)作为抗疟化合物的类型和潜力的研究结果,在楠绒省Tanggamus Regency Semaka区的Pekon Bangunrejo, Waypanas和Betung中发现了14种竹子植物。当地社区/民族植物学的一些竹子品种被用作发烧患者的退烧药。需要进一步的试验来确定从竹子中提取的化合物,这些化合物在抗疟疾治疗的药物发现和开发中发挥重要作用。确定具有抗疟潜力的化合物的进一步测试之一是通过植物化学筛选。植物化学筛选的目的是根据竹子的传统用途或当地智慧从竹子中分离出生物活性化合物。该研究于2022年1月至2022年6月在楠榜省Metro City Muhammadiyah Metro University的PMIPA生物学实验室进行。这种类型的研究是描述性质的。观察黄酮、生物碱定量试验、黄酮、生物碱、皂苷、单宁定性试验中活性物质的颜色和含量。试验重复进行1次。观察和文件活动形式的原始数据。以观察的形式进行植物化学筛选,以区分次生代谢产物的含量形式进行黄酮和生物碱的定量检测,黄酮、生物碱、皂苷和单宁的定性检测。从竹叶中分离得到3种植物化学成分,即黄酮类化合物、生物碱、皂苷和单宁。在黄竹中,斑竹(Bambusa vulgaris var. striata)。(前林德尔)检测出皂苷,黄酮和单宁阳性。竹笋总皂苷、生物碱和单宁检测均呈阳性。竹叶中总皂苷、生物碱和黄酮的检测结果均为阳性。其他的研究需要从竹子身体的其他部分,如茎、根和芽中寻找化合物。
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IDENTIFIKASI SENYAWA BIOAKTIF BEBERAPA JENIS DAUN BAMBU YANG BERPOTENSI SEBAGAI ANTIMALARIA
Bamboo has potential as medicine. Based on the results of research conducted by Agus & Zen (2020) regarding the Identification of Types and Potentials of Bamboo ( Bambusa sp) as Antimalarial Compounds, 14 species of bamboo plants were found scattered in Pekon Bangunrejo, Waypanas, and Betung, Semaka District, Tanggamus Regency, Lampung Province. Some of the bamboo species by the local community / ethnobotany are used as fever reducers in fever sufferers. Further tests are needed to determine the compounds derived from bamboo which play an important role in drug discovery and development of antimalarial treatment. One of the further tests to determine compounds that have the potential as antimalarials is by means of phytochemical screening. Phytochemical screening aims to isolate bioactive compounds from bamboo based on their traditional use or local wisdom. This research was carried out at the PMIPA Biology laboratory, Muhammadiyah Metro University, Metro City, Lampung Province from January 2022 to June 2022. This type of research is descriptive qualitative. Parameters observed were color and content of bioactive compounds in the quantitative test of flavonoids and alkaloids, qualitative tests of flavonoids, alkaloids, saponins and tannins. The test was carried out for 1 time of replication. Primary data in the form of observation and documentation activities. Observations in the form of phytochemical screening to distinguish the content of secondary metabolites in the form of quantitative tests of flavonoids and alkaloids, qualitative tests of flavonoids, alkaloids, saponins and tannins. The results obtained phytochemicals from 3 types of bamboo leaves, namely flavonoid compounds, alkaloids, saponins, and tannins. In yellow bamboo, Bambusa vulgaris var. striata (Lodd. ex Lindl.) detected positive for saponins, flavones and tannins. Bambu apus Gigantochloa apus (Kurz) was detected positive for saponins, alkaloids and tannins. Bamboo alar/cangkoreh leaves of Dinochloa scandens (Blume ex Nees Kuntze) were detected positive for saponins, alkaloids and flavones. Other research needs to be done to look for chemical compounds from other parts of the bamboo body, such as stems, roots, and shoots.
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