Sergio Charles-Lozoya , Gibran Ruíz-Zenteno , María E. Lizcano-Martínez , Héctor Cobos-Aguilar , Joél León-Ruíz , Jesús Domínguez-Delgado
{"title":"单纯用抗真菌药物治疗椎体球虫菌病伴机械不稳定:1例报告","authors":"Sergio Charles-Lozoya , Gibran Ruíz-Zenteno , María E. Lizcano-Martínez , Héctor Cobos-Aguilar , Joél León-Ruíz , Jesús Domínguez-Delgado","doi":"10.1016/j.mmcr.2023.100615","DOIUrl":null,"url":null,"abstract":"<div><p>Surgical treatment of vertebral coccidioidomycosis presents a challenge, with an unpredictable course and uncertain results. We present a 52-year-old man with disseminated infection due to coccidioidomycosis in the thoracolumbar spine, with vertebral instability, and deferral surgical treatment due to SARS-CoV-2 contingency. Treatment with itraconazole was initiated, followed by liposomal amphotericin B and fluconazole due to a relapse. The patient was discharged long-term with voriconazole. The axial pain improved without neurological deficits. Surgical treatment was not required. 2012 Elsevier Ltd. All rights reserved.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"42 ","pages":"Article 100615"},"PeriodicalIF":1.6000,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211753923000477/pdfft?md5=3d11cc44d084849d4f7e592184ac3fb1&pid=1-s2.0-S2211753923000477-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Vertebral coccidioidomycosis with mechanical instability treated solely with antifungals: A case report\",\"authors\":\"Sergio Charles-Lozoya , Gibran Ruíz-Zenteno , María E. Lizcano-Martínez , Héctor Cobos-Aguilar , Joél León-Ruíz , Jesús Domínguez-Delgado\",\"doi\":\"10.1016/j.mmcr.2023.100615\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Surgical treatment of vertebral coccidioidomycosis presents a challenge, with an unpredictable course and uncertain results. We present a 52-year-old man with disseminated infection due to coccidioidomycosis in the thoracolumbar spine, with vertebral instability, and deferral surgical treatment due to SARS-CoV-2 contingency. Treatment with itraconazole was initiated, followed by liposomal amphotericin B and fluconazole due to a relapse. The patient was discharged long-term with voriconazole. The axial pain improved without neurological deficits. Surgical treatment was not required. 2012 Elsevier Ltd. All rights reserved.</p></div>\",\"PeriodicalId\":51724,\"journal\":{\"name\":\"Medical Mycology Case Reports\",\"volume\":\"42 \",\"pages\":\"Article 100615\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2023-11-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2211753923000477/pdfft?md5=3d11cc44d084849d4f7e592184ac3fb1&pid=1-s2.0-S2211753923000477-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Mycology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2211753923000477\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Mycology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211753923000477","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
Vertebral coccidioidomycosis with mechanical instability treated solely with antifungals: A case report
Surgical treatment of vertebral coccidioidomycosis presents a challenge, with an unpredictable course and uncertain results. We present a 52-year-old man with disseminated infection due to coccidioidomycosis in the thoracolumbar spine, with vertebral instability, and deferral surgical treatment due to SARS-CoV-2 contingency. Treatment with itraconazole was initiated, followed by liposomal amphotericin B and fluconazole due to a relapse. The patient was discharged long-term with voriconazole. The axial pain improved without neurological deficits. Surgical treatment was not required. 2012 Elsevier Ltd. All rights reserved.
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