铜绿假单胞菌在食品安全和公共卫生中的重要性

Soner Tutun, Özen Yurdakul
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摘要

铜绿假单胞菌(P. aeruginosa)是假单胞菌中致病性最强的一种,是一种引起机会性感染的细菌,对宿主组织造成重大损害。铜绿假单胞菌对抗生素具有耐药性,也会在人类和动物中引起致命感染。铜绿假单胞菌引起的感染很难治疗,因为它在环境中迅速增殖,并能形成生物膜,从而对抗生素产生耐药性。铜绿假单胞菌的主要毒力因素之一是其对宿主组织的直接损伤,破坏宿主的防御机制。铜绿假单胞菌是一种食源性病原体,经常在肉类、牛奶、水果、蔬菜和水等各种食物中检测到。近年来,铜绿假单胞菌引起的食源性污染明显增加。由于铜绿假单胞菌可对大多数抗菌药物产生耐药性,因此迫切需要采取新的措施来治疗由该药物引起的感染患者。本文将对铜绿假单胞菌这一对公共卫生具有重要意义的生物进行综述。
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Importance of Pseudomonas aeruginosa in Food Safety and Public Health
Pseudomonas aeruginosa (P. aeruginosa), the most pathogenic species among the pseudomonas species, is a bacterium that causes opportunistic infections resulting in significant damage to host tissues. P. aeruginosa, which is resistant to antibiotics, also causes fatal infection in human and animals. Infections caused by P. aeruginosa are difficult to treat due to its rapid proliferation in the environment and its ability to form biofilms that confer resistance to antibiotics. One of the main virulence factors of P. aeruginosa is its direct damage to host tissues, which disrupts the host’s defense mechanisms. P. aeruginosa is a food-borne pathogen often detected in various food groups such as meat, milk, fruit, vegetables, and water. In recent years, there has been a noticeable rise in food-borne contamination with P. aeruginosa. New measures are urgently needed in the treatment of patients with infections due to this agent, since P. aeruginosa can develop resistance to most antibacterials. In this review, general information about P. aeruginosa, which has gained importance for public health, will be given.
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