Accurate Fetal QRS-Complex Classification from Abdominal Electrocardiogram Using Deep Learning

Abstract Fetal heart monitoring during pregnancy plays a critical role in diagnosing congenital heart disease (CHD). A noninvasive fetal electrocardiogram (fECG) provides additional clinical information for fetal heart monitoring. To date, the analysis of noninvasive fECG is challenging due to the cancellation of maternal QRS-complexes, despite significant advances in electrocardiography. Fetal QRS-complex is highly considered to measure fetal heart rate to detect some fetal abnormalities such as arrhythmia. In this study, we proposed a deep learning (DL) framework that stacked a convolutional layer and bidirectional long short-term memory for fetal QRS-complexes classification. The fECG signals are first preprocessed using discrete wavelet transform (DWT) to remove the noise or inferences. The following step beats and QRS-complex segmentation. The last step is fetal QRS-complex classification based on DL. In the experiment of Physionet/Computing in Cardiology Challenge 2013, this study achieved 100% accuracy, sensitivity, specificity, precision, and F1-score. A stacked DL model demonstrates an effective tool for fetal QRS-complex classification and contributes to clinical applications for long-term maternal and fetal monitoring.