GtoPdb v.2023.1中的冠状病毒蛋白

Stephen P.H. Alexander, Jonathan K. Ball, Theocharis Tsoleridis
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引用次数: 0

摘要

冠状病毒是大的,通常是球形的,包膜的单链阳性RNA病毒,大小从80-220纳米不等。它们的基因组和蛋白质结构高度保守。在过去的20年里,已经出现了三种冠状病毒作为严重的人类病原体:2002-2003年爆发的SARS-CoV被确定为病原体,2012年出现了中东呼吸综合征(MERS)冠状病毒,2019-2020年出现了新型冠状病毒SARS-CoV-2。SARS-CoV-2是导致COVID-19传染病的病毒(世卫组织《2020年技术指南》)。
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Coronavirus (CoV) proteins in GtoPdb v.2023.1
Coronaviruses are large, often spherical, enveloped, single-stranded positive-sense RNA viruses, ranging in size from 80-220 nm. Their genomes and protein structures are highly conserved. Three coronaviruses have emerged over the last 20 years as serious human pathogens: SARS-CoV was identified as the causative agent in an outbreak in 2002-2003, Middle East respiratory syndrome (MERS) CoV emerged in 2012 and the novel coronavirus SARS-CoV-2 emerged in 2019-2020. SARS-CoV-2 is the virus responsible for the infectious disease termed COVID-19 (WHO Technical Guidance 2020).
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