Rohadi Muhammad Rosyidi, Bambang Priyanto, Januarman J, Zakiuddin Abd. Azam, Dewa Putu Wisnu Wardhana
{"title":"减压颅骨切除术与创伤性脑损伤预后的关系:一项单中心研究","authors":"Rohadi Muhammad Rosyidi, Bambang Priyanto, Januarman J, Zakiuddin Abd. Azam, Dewa Putu Wisnu Wardhana","doi":"10.13005/bpj/2725","DOIUrl":null,"url":null,"abstract":"Traumatic Brain Injury (TBI) has significantly increased both mortality and morbidity in developed and developing countries. Decompressive Craniectomy (DC) is an option when conventional treatments fail to reduce intracranial pressure (ICP) when brain edema occurs in TBI. This study aims to determine the relationship between DC and patients with TBI in West Nusa Tenggara Provincial Hospital whose outcome was assessed with Glasgow Outcome Scale Extended (GOSE) and modified Rankin Scale (mRS). A total of 41 TBI patients who underwent DC were included in the study. Univariate analysis revealed that men made up the majority of the subjects, with 26 people (63.4%) compared to 15 women (36.3%). Traffic accidents (82.9%), falling (12.2%), and being crushed (4.9%) accounted for the majority of the causes of TBI. Bivariate analysis showed that pupillary reflex, length of stay, and Glasgow Coma Scale at discharge from the hospital were associated with outcome (p=0.002; p=0.000; p=0.000 respectively), GOSE (p=0.001; p=0.000; p=0.000 respectively), and mRS (p=0.001; p=0.000; p=0.000 respectively). Other factors such as gender, age, trauma mechanism, GCS admission, and operation time, however, did not significantly affect the outcome, GOSE, or mRS.","PeriodicalId":9054,"journal":{"name":"Biomedical and Pharmacology Journal","volume":"30 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Relationship between Decompressive Craniectomy and Traumatic Brain Injury Outcomes: A Single-Center Study\",\"authors\":\"Rohadi Muhammad Rosyidi, Bambang Priyanto, Januarman J, Zakiuddin Abd. Azam, Dewa Putu Wisnu Wardhana\",\"doi\":\"10.13005/bpj/2725\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Traumatic Brain Injury (TBI) has significantly increased both mortality and morbidity in developed and developing countries. Decompressive Craniectomy (DC) is an option when conventional treatments fail to reduce intracranial pressure (ICP) when brain edema occurs in TBI. This study aims to determine the relationship between DC and patients with TBI in West Nusa Tenggara Provincial Hospital whose outcome was assessed with Glasgow Outcome Scale Extended (GOSE) and modified Rankin Scale (mRS). A total of 41 TBI patients who underwent DC were included in the study. Univariate analysis revealed that men made up the majority of the subjects, with 26 people (63.4%) compared to 15 women (36.3%). Traffic accidents (82.9%), falling (12.2%), and being crushed (4.9%) accounted for the majority of the causes of TBI. Bivariate analysis showed that pupillary reflex, length of stay, and Glasgow Coma Scale at discharge from the hospital were associated with outcome (p=0.002; p=0.000; p=0.000 respectively), GOSE (p=0.001; p=0.000; p=0.000 respectively), and mRS (p=0.001; p=0.000; p=0.000 respectively). Other factors such as gender, age, trauma mechanism, GCS admission, and operation time, however, did not significantly affect the outcome, GOSE, or mRS.\",\"PeriodicalId\":9054,\"journal\":{\"name\":\"Biomedical and Pharmacology Journal\",\"volume\":\"30 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomedical and Pharmacology Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.13005/bpj/2725\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical and Pharmacology Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.13005/bpj/2725","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
Relationship between Decompressive Craniectomy and Traumatic Brain Injury Outcomes: A Single-Center Study
Traumatic Brain Injury (TBI) has significantly increased both mortality and morbidity in developed and developing countries. Decompressive Craniectomy (DC) is an option when conventional treatments fail to reduce intracranial pressure (ICP) when brain edema occurs in TBI. This study aims to determine the relationship between DC and patients with TBI in West Nusa Tenggara Provincial Hospital whose outcome was assessed with Glasgow Outcome Scale Extended (GOSE) and modified Rankin Scale (mRS). A total of 41 TBI patients who underwent DC were included in the study. Univariate analysis revealed that men made up the majority of the subjects, with 26 people (63.4%) compared to 15 women (36.3%). Traffic accidents (82.9%), falling (12.2%), and being crushed (4.9%) accounted for the majority of the causes of TBI. Bivariate analysis showed that pupillary reflex, length of stay, and Glasgow Coma Scale at discharge from the hospital were associated with outcome (p=0.002; p=0.000; p=0.000 respectively), GOSE (p=0.001; p=0.000; p=0.000 respectively), and mRS (p=0.001; p=0.000; p=0.000 respectively). Other factors such as gender, age, trauma mechanism, GCS admission, and operation time, however, did not significantly affect the outcome, GOSE, or mRS.
期刊介绍:
Biomedical and Pharmacology Journal (BPJ) is an International Peer Reviewed Research Journal in English language whose frequency is quarterly. The journal seeks to promote research, exchange of scientific information, consideration of regulatory mechanisms that affect drug development and utilization, and medical education. BPJ take much care in making your article published without much delay with your kind cooperation and support. Research papers, review articles, short communications, news are welcomed provided they demonstrate new findings of relevance to the field as a whole. All articles will be peer-reviewed and will find a place in Biomedical and Pharmacology Journal based on the merit and innovativeness of the research work. BPJ hopes that Researchers, Research scholars, Academician, Industrialists etc. would make use of this journal for the development of science and technology. Topics of interest include, but are not limited to: Biochemistry Genetics Microbiology and virology Molecular, cellular and cancer biology Neurosciences Pharmacology Drug Discovery Cardiovascular Pharmacology Neuropharmacology Molecular & Cellular Mechanisms Immunology & Inflammation Pharmacy.