减压颅骨切除术与创伤性脑损伤预后的关系:一项单中心研究

Q3 Pharmacology, Toxicology and Pharmaceutics Biomedical and Pharmacology Journal Pub Date : 2023-09-30 DOI:10.13005/bpj/2725
Rohadi Muhammad Rosyidi, Bambang Priyanto, Januarman J, Zakiuddin Abd. Azam, Dewa Putu Wisnu Wardhana
{"title":"减压颅骨切除术与创伤性脑损伤预后的关系:一项单中心研究","authors":"Rohadi Muhammad Rosyidi, Bambang Priyanto, Januarman J, Zakiuddin Abd. Azam, Dewa Putu Wisnu Wardhana","doi":"10.13005/bpj/2725","DOIUrl":null,"url":null,"abstract":"Traumatic Brain Injury (TBI) has significantly increased both mortality and morbidity in developed and developing countries. Decompressive Craniectomy (DC) is an option when conventional treatments fail to reduce intracranial pressure (ICP) when brain edema occurs in TBI. This study aims to determine the relationship between DC and patients with TBI in West Nusa Tenggara Provincial Hospital whose outcome was assessed with Glasgow Outcome Scale Extended (GOSE) and modified Rankin Scale (mRS). A total of 41 TBI patients who underwent DC were included in the study. Univariate analysis revealed that men made up the majority of the subjects, with 26 people (63.4%) compared to 15 women (36.3%). Traffic accidents (82.9%), falling (12.2%), and being crushed (4.9%) accounted for the majority of the causes of TBI. Bivariate analysis showed that pupillary reflex, length of stay, and Glasgow Coma Scale at discharge from the hospital were associated with outcome (p=0.002; p=0.000; p=0.000 respectively), GOSE (p=0.001; p=0.000; p=0.000 respectively), and mRS (p=0.001; p=0.000; p=0.000 respectively). Other factors such as gender, age, trauma mechanism, GCS admission, and operation time, however, did not significantly affect the outcome, GOSE, or mRS.","PeriodicalId":9054,"journal":{"name":"Biomedical and Pharmacology Journal","volume":"30 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Relationship between Decompressive Craniectomy and Traumatic Brain Injury Outcomes: A Single-Center Study\",\"authors\":\"Rohadi Muhammad Rosyidi, Bambang Priyanto, Januarman J, Zakiuddin Abd. Azam, Dewa Putu Wisnu Wardhana\",\"doi\":\"10.13005/bpj/2725\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Traumatic Brain Injury (TBI) has significantly increased both mortality and morbidity in developed and developing countries. Decompressive Craniectomy (DC) is an option when conventional treatments fail to reduce intracranial pressure (ICP) when brain edema occurs in TBI. This study aims to determine the relationship between DC and patients with TBI in West Nusa Tenggara Provincial Hospital whose outcome was assessed with Glasgow Outcome Scale Extended (GOSE) and modified Rankin Scale (mRS). A total of 41 TBI patients who underwent DC were included in the study. Univariate analysis revealed that men made up the majority of the subjects, with 26 people (63.4%) compared to 15 women (36.3%). Traffic accidents (82.9%), falling (12.2%), and being crushed (4.9%) accounted for the majority of the causes of TBI. Bivariate analysis showed that pupillary reflex, length of stay, and Glasgow Coma Scale at discharge from the hospital were associated with outcome (p=0.002; p=0.000; p=0.000 respectively), GOSE (p=0.001; p=0.000; p=0.000 respectively), and mRS (p=0.001; p=0.000; p=0.000 respectively). Other factors such as gender, age, trauma mechanism, GCS admission, and operation time, however, did not significantly affect the outcome, GOSE, or mRS.\",\"PeriodicalId\":9054,\"journal\":{\"name\":\"Biomedical and Pharmacology Journal\",\"volume\":\"30 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomedical and Pharmacology Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.13005/bpj/2725\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical and Pharmacology Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.13005/bpj/2725","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
引用次数: 0

摘要

创伤性脑损伤(TBI)在发达国家和发展中国家的死亡率和发病率都显著增加。当常规治疗无法降低颅内压(ICP)时,减压颅骨切除术(DC)是一种选择。本研究旨在确定DC与西努沙登加拉省医院TBI患者的关系,这些患者的预后采用格拉斯哥结局量表扩展版(GOSE)和改良Rankin量表(mRS)进行评估。共有41名接受DC治疗的TBI患者被纳入研究。单变量分析显示,男性占大多数,有26人(63.4%),而女性为15人(36.3%)。交通事故(82.9%)、坠落(12.2%)和被压伤(4.9%)是造成TBI的主要原因。双变量分析显示,瞳孔反射、住院时间和出院时格拉斯哥昏迷量表与结果相关(p=0.002;p = 0.000;p=0.000), GOSE (p=0.001;p = 0.000;p=0.000), mRS (p=0.001;p = 0.000;p = 0.000)。其他因素如性别、年龄、创伤机制、GCS入院和手术时间对预后、GOSE或mRS均无显著影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Relationship between Decompressive Craniectomy and Traumatic Brain Injury Outcomes: A Single-Center Study
Traumatic Brain Injury (TBI) has significantly increased both mortality and morbidity in developed and developing countries. Decompressive Craniectomy (DC) is an option when conventional treatments fail to reduce intracranial pressure (ICP) when brain edema occurs in TBI. This study aims to determine the relationship between DC and patients with TBI in West Nusa Tenggara Provincial Hospital whose outcome was assessed with Glasgow Outcome Scale Extended (GOSE) and modified Rankin Scale (mRS). A total of 41 TBI patients who underwent DC were included in the study. Univariate analysis revealed that men made up the majority of the subjects, with 26 people (63.4%) compared to 15 women (36.3%). Traffic accidents (82.9%), falling (12.2%), and being crushed (4.9%) accounted for the majority of the causes of TBI. Bivariate analysis showed that pupillary reflex, length of stay, and Glasgow Coma Scale at discharge from the hospital were associated with outcome (p=0.002; p=0.000; p=0.000 respectively), GOSE (p=0.001; p=0.000; p=0.000 respectively), and mRS (p=0.001; p=0.000; p=0.000 respectively). Other factors such as gender, age, trauma mechanism, GCS admission, and operation time, however, did not significantly affect the outcome, GOSE, or mRS.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Biomedical and Pharmacology Journal
Biomedical and Pharmacology Journal Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
1.20
自引率
0.00%
发文量
189
期刊介绍: Biomedical and Pharmacology Journal (BPJ) is an International Peer Reviewed Research Journal in English language whose frequency is quarterly. The journal seeks to promote research, exchange of scientific information, consideration of regulatory mechanisms that affect drug development and utilization, and medical education. BPJ take much care in making your article published without much delay with your kind cooperation and support. Research papers, review articles, short communications, news are welcomed provided they demonstrate new findings of relevance to the field as a whole. All articles will be peer-reviewed and will find a place in Biomedical and Pharmacology Journal based on the merit and innovativeness of the research work. BPJ hopes that Researchers, Research scholars, Academician, Industrialists etc. would make use of this journal for the development of science and technology. Topics of interest include, but are not limited to: Biochemistry Genetics Microbiology and virology Molecular, cellular and cancer biology Neurosciences Pharmacology Drug Discovery Cardiovascular Pharmacology Neuropharmacology Molecular & Cellular Mechanisms Immunology & Inflammation Pharmacy.
期刊最新文献
A Comparison of the Recovery Profile of Dexmedetomidine When Administered by Different Routes in Patients Undergoing Laparoscopic Cholecystectomy – A Randomized Controlled Trial Health Literacy in People Living with Human Immunodeficiency Virus Infection: A Narrative Review Targeted Pharmaceutical Analysis of Antibiotic Use by Risk Criteria in Patients Hospitalized in the Infectious and Tropical Diseases Department at Treichville Teaching Hospital (Abidjan, Côte d'Ivoire) Hybrid Model: Deep Learning method for Early Detection of Alzheimer’s disease from MRI images Autologous Platelet-Rich Plasma: A Potential Therapy to Mitigate Severe Covid-19 Manifestations
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1