精神分裂症、自闭症及形式思维障碍患者语言特征的计算分析

Takeshi Saga, Hiroki Tanaka, Satoshi Nakamura
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摘要

形式思维障碍(FTD)是一组影响语言和思维的认知症状,可以通过语言来观察。FTD见于发育性或精神障碍,如自闭症谱系障碍(ASD)或精神分裂症,及其相关的分裂型人格障碍(SPD)。40多年来,研究人员一直致力于通过计算分析来早期发现这些症状,并开发出更好的治疗方法。本文通过大众众包服务收集了一个日本音频报告数据集,其中包含与ASD和SPD相关的分数标签。我们使用第二版社会反应量表(SRS2)和分裂型人格问卷(SPQ)测量语言特征,包括SPQ中的奇数言语子量表来量化FTD症状。我们通过基于机器学习的分数预测研究了以下四个研究问题:(RQ1)分裂型和自闭症的测量是如何相关的?(RQ2)什么是最适合引发FTD症状的任务?(RQ3)言语长度是否影响FTD症状的引发?(RQ4)哪些特性对于捕捉FTD症状至关重要?我们证实了ftd相关的子量表,奇怪的言语,与总SPQ和SRS得分显著相关,尽管它们本身没有显著相关。在任务方面,我们的结果确定了最负性记忆诱发FTD的有效性。此外,我们证实,较长的言语引发更多的FTD症状,因为来自SPQ的FTD相关亚量表奇数言语的得分预测性能提高。我们的消融研究证实了虚词及其抽象和时间特征对ftd相关奇语估计的重要性。相比之下,基于嵌入的特征仅在SRS预测中有效,而内容词仅在SPQ预测中有效,这一结果暗示了spd样症状和asd样症状的差异。本文中使用的数据和程序可以在这里找到:https://sites.google.com/view/sagatake/resource。
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Computational analyses of linguistic features with schizophrenic and autistic traits along with formal thought disorders
Formal Thought Disorder (FTD), which is a group of symptoms in cognition that affects language and thought, can be observed through language. FTD is seen across such developmental or psychiatric disorders as Autism Spectrum Disorder (ASD) or Schizophrenia, and its related Schizotypal Personality Disorder (SPD). Researchers have worked on computational analyses for the early detection of such symptoms and to develop better treatments more than 40 years. This paper collected a Japanese audio-report dataset with score labels related to ASD and SPD through a crowd-sourcing service from the general population. We measured language characteristics with the 2nd edition of the Social Responsiveness Scale (SRS2) and the Schizotypal Personality Questionnaire (SPQ), including an odd speech subscale from SPQ to quantize the FTD symptoms. We investigated the following four research questions through machine-learning-based score predictions: (RQ1) How are schizotypal and autistic measures correlated? (RQ2) What is the most suitable task to elicit FTD symptoms? (RQ3) Does the length of speech affect the elicitation of FTD symptoms? (RQ4) Which features are critical for capturing FTD symptoms? We confirmed that an FTD-related subscale, odd speech, was significantly correlated with both the total SPQ and SRS scores, although they themselves were not correlated significantly. In terms of the tasks, our result identified the effectiveness of FTD elicitation by the most negative memory. Furthermore, we confirmed that longer speech elicited more FTD symptoms as the increased score prediction performance of an FTD-related subscale odd speech from SPQ. Our ablation study confirmed the importance of function words and both the abstract and temporal features for FTD-related odd speech estimation. In contrast, embedding-based features were effective only in the SRS predictions, and content words were effective only in the SPQ predictions, a result that implies the differences of SPD-like and ASD-like symptoms. Data and programs used in this paper can be found here: https://sites.google.com/view/sagatake/resource.
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