高脂血症:文献综述

Swapnil S. Lad, Swati U. Kolhe, Omkar A. Devade, Asawari P. Mansabdar
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引用次数: 0

摘要

自古以来,人们就用植物来治疗各种感染和/或疾病。随着目前合成药物的发展,植物药物经常处于治疗方式的边缘。然而,人们逐渐认识到,合成治疗剂有一些局限性,特别是在持续的慢性疾病,如高脂血症。高脂血症是一种以至少一种血浆脂质增加为特征的疾病,包括胆固醇、甘油三酯、血浆脂蛋白如低密度脂蛋白(LDL)和极低密度脂蛋白(VLDL),同时高密度脂蛋白(HDL)水平降低。研究不断发现更多的现有药物和一些新的有用的目标正在研究高脂血症。在当前的综述中,高脂血症的类型,脂质代谢,高脂血症的原因和危险因素进行了解释,以及植物源性生物活性物质和提取物在过去15年中已被证明具有治疗高脂血症的潜力进行了讨论。
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Hyperlipidaemia: A Review of Literature
Since the beginning of time people have used plants as a solution for different infections and/or diseases. With the approach of current synthetic medicines, plant medication has frequently been subjected to the edge of therapeutic modalities. However, it is progressively being recognized that the synthetic therapeutic agents have a few limitations particularly in ongoing chronic illnesses like hyperlipidaemia. Hyperlipidaemia is an ailment characterised by an expansion in at least one of the plasma lipids, including cholesterol, triglycerides, plasma lipoproteins such as low density lipoprotein (LDL) and very low density lipoprotein (VLDL) alongside diminished high-density lipoprotein (HDL) levels. Research is continuous to find more current medications and a few novel helpful targets are being investigated for hyperlipidaemia. In the current review, the types of hyperlipidaemias, lipid metabolism, causes and risk factors of hyperlipidaemia has been explained along side the plant derived bioactiveand extracts that have been demonstrated in the past 15 years to have a potential in treatment of hyperlipidaemia has been discussed.
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