Relationship between disturbances in the blood immunobiochemistry profile of pregnant cows and the incidence of calves with rotaviral infection

The conducted studies have established that in the group of deep-calving cows with normal and elevated biochemical parameters, an increase in the content of total protein, glucose, concentration of inorganic calcium, an increase in the activity of ALT and alkaline phosphatase was observed. From immunological indicators, the number of T- and B-cells increased. Here, factors that increase the natural resistance of the body of cows, namely, the increase in bactericidal and lysozyme activity of blood serum, are of great importance. In the group of deep-calving cows, where immunobiochemical parameters in most cases were lower than control analogues, the concentration of total protein, glucose, triglycerides, cholesterol, carotene, AST and alkaline phosphatase activity decreased most intensively. Conducting immunological monitoring, a decrease in the number of T- and B-immunocompetent cells was established, bactericidal and lysozyme activity and an indicator of phagocytic activity fell. Draws attention to the weakening of the cellular link of immunity, which indicates the depletion of T-lymphocytes and the development of immunodeficiency states in females. Calves obtained from cow mothers with low immunobiochemical parameters were much more likely to become ill with rotavirus infection, and in half of the diseased calves (26.6 %) a severe form was noted, and in 20 % of the diseased calves a moderate severity of the disease was diagnosed.