频率对间质性高热疗法治疗肉瘤肿瘤热传播的影响

IF 0.4 Q4 ENGINEERING, MULTIDISCIPLINARY International Journal of Integrated Engineering Pub Date : 2023-08-28 DOI:10.30880/ijie.2023.15.04.015
Slamet Wahyudi, Putu Hadi Setyarini, Isa Tan Kretapaswakara
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引用次数: 0

摘要

频率是用来计算波的。在生物医学科学中,频率在传递热量和生物传热中起着重要作用。在生物热传递研究中,热传递在人体内可以作为一种治疗方法,如治疗。在通常高于40摄氏度的高温下,细胞会死亡,不能再发育,这被称为高热疗法。这种疗法通常用于具有杀死肿瘤细胞功能的医学中。热疗有外热、腔热和间质热三种不同,间质热疗的愈合能力较好,因为热直接传递到肿瘤组织,最大限度地减少了没有肿瘤暴露在治疗温度(40-46℃)下的组织。然后采用热疗的间隙法对人体表皮、真皮、脂肪、肌肉、骨骼五层进行传热分析,并受频率影响进行研究,频率值为434;915;2450mhz采用有限元法在两轴向非稳态条件下完成。本研究表明,频率会影响人体五层温度分布的数值。给定的频率值越大,温度越容易分布,因为如果频率增加,频率将提供更大的电磁波。采用间质热疗可以使治疗温度更稳定,因为针是热传递的介质。间质性治疗研究的方法是对手肿瘤肉瘤进行针刺治疗。这看起来很简单,但需要更多的准备,如电压,频率,测量患者的代谢和血液灌注,并做出分析测量来进行治疗。研究结果表明,间质热传播的热量稳定在40-46℃,这是肿瘤治疗的治疗温度,并且随着源输入功率和频率的提高,该温度会升高。研究得出结论,间质热疗对肉瘤肿瘤特别是手部肿瘤肉瘤是有效的,因为在治疗温度下热量在肿瘤上很好地扩散,本研究中应用的频率是治疗的最佳选择,因为它可以将温度稳定在40-46℃左右。
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Effect of Frequency on Heat Spread by Interstitial Hypertemia Treatment Method for The Treatment of Sarcoma Tumors
Frequency is a thing to calculate a wave. In biomedical science, frequency plays an important role in delivering heat as in bioheat transfer. In bioheat transfer studies, heat transfer in the human body can be used as one way of treatment such as therapy. At high temperatures that are usually above 40oC, the cell will die and cannot develop again this is called hyperthemia therapy. This therapy is commonly used in medicine with the function to kill tumor cells. There are 3 differences in hyperthemia therapy there are external, cavity and intersitital and interstitial hyperthermia therapy has better healing ability because heatis directly delivered to the tumor tissue to minimize tissue that no tumor is exposed to therapeutic temperature (40-46oC). Then the author will conduct a study with an analysis of heat transfer carried out on five layers of the human body, namely the epidermis, dermis, fat, muscle, and bones by applying the interstitial method of hyperthermia therapy and influenced by frequencies with a value of 434; 915; 2450 MHz completed using finite element method with unsteady state conditions in two axial dimensions. This study showed that frequency affects the value of temperature distribution in the five layers of the body. The greater the frequency value given, the more easily distributed the temperature will be because the frequency will provide greater electromagnetic waves if the frequency is increased.With interstitial hyperthermia would be optimize the therapeutic temperature more stable because of the needle as the media of the heat transfer. The methods of the interstitial treatment research areinsert the needle to the sarcoma hand tumor. This look very simple but need more preparation like, voltage, frequency, measure the metabolic and blood perfusion of the patient and made a analytics measure to do the treatment. The result of the research is heat that spread by interstitial hyperthermia are stable at 40-46oC which is the therapeutic temperature of tumor treatment,and the temperature will be increase with upgrade the power input of the source and the frequencies. The research has a conclusion that interstitial hyperthermia on sarcoma tumor especially on hand tumor sarcoma is effectively because the heat is spread well on the tumor at therapeutic temperature and frequencies that applied in this research is optimal for the treatment because it could keep the temperature steady on around 40-46oC.
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来源期刊
International Journal of Integrated Engineering
International Journal of Integrated Engineering ENGINEERING, MULTIDISCIPLINARY-
CiteScore
1.40
自引率
0.00%
发文量
57
期刊介绍: The International Journal of Integrated Engineering (IJIE) is a single blind peer reviewed journal which publishes 3 times a year since 2009. The journal is dedicated to various issues focusing on 3 different fields which are:- Civil and Environmental Engineering. Original contributions for civil and environmental engineering related practices will be publishing under this category and as the nucleus of the journal contents. The journal publishes a wide range of research and application papers which describe laboratory and numerical investigations or report on full scale projects. Electrical and Electronic Engineering. It stands as a international medium for the publication of original papers concerned with the electrical and electronic engineering. The journal aims to present to the international community important results of work in this field, whether in the form of research, development, application or design. Mechanical, Materials and Manufacturing Engineering. It is a platform for the publication and dissemination of original work which contributes to the understanding of the main disciplines underpinning the mechanical, materials and manufacturing engineering. Original contributions giving insight into engineering practices related to mechanical, materials and manufacturing engineering form the core of the journal contents.
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