{"title":"早期绝经和卵巢功能不全与痴呆风险增加相关:一项系统回顾和荟萃分析","authors":"Eleni Karamitrou, Panagiotis Anagnostis, Konstantina Vaitsi, Loukas Athanasiadis, Dimitrios Goulis","doi":"10.1016/j.maturitas.2023.04.177","DOIUrl":null,"url":null,"abstract":"Background / Aims: As estrogens play a neuroprotective role, the decline in their concentrations during menopause may compromise cognitive function in postmenopausal women. Whether early menopause (EM) is associated with an increased risk of dementia remains unclear. The purpose of this study was to systematically review and meta-analyze current evidence regarding the association between EM or premature ovarian insufficiency (POI) and the risk of dementia of any type.","PeriodicalId":94131,"journal":{"name":"Maturitas","volume":"46 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Early menopause and premature ovarian insufficiency are associated with increased risk of dementia: a systematic review and meta-analysis\",\"authors\":\"Eleni Karamitrou, Panagiotis Anagnostis, Konstantina Vaitsi, Loukas Athanasiadis, Dimitrios Goulis\",\"doi\":\"10.1016/j.maturitas.2023.04.177\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background / Aims: As estrogens play a neuroprotective role, the decline in their concentrations during menopause may compromise cognitive function in postmenopausal women. Whether early menopause (EM) is associated with an increased risk of dementia remains unclear. The purpose of this study was to systematically review and meta-analyze current evidence regarding the association between EM or premature ovarian insufficiency (POI) and the risk of dementia of any type.\",\"PeriodicalId\":94131,\"journal\":{\"name\":\"Maturitas\",\"volume\":\"46 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Maturitas\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.maturitas.2023.04.177\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Maturitas","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.maturitas.2023.04.177","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Early menopause and premature ovarian insufficiency are associated with increased risk of dementia: a systematic review and meta-analysis
Background / Aims: As estrogens play a neuroprotective role, the decline in their concentrations during menopause may compromise cognitive function in postmenopausal women. Whether early menopause (EM) is associated with an increased risk of dementia remains unclear. The purpose of this study was to systematically review and meta-analyze current evidence regarding the association between EM or premature ovarian insufficiency (POI) and the risk of dementia of any type.
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